超氧化物歧化酶在脑中的区域及亚细胞分布
Regional and subcellular distribution of superoxide dismutase in brain.
作者信息
Loomis T C, Yee G, Stahl W L
出版信息
Experientia. 1976 Nov 15;32(11):1374-6. doi: 10.1007/BF01937382.
PMID:136361
Abstract
Superoxide dismutase has been found to be widely distributed and of approximately the same specific activity in all regions of human brain examined. It is not reduced during degeneration of the basal ganglia in Huntington's Chorea. After subcellular fractionation of human and guinea-pig cerebral cortex, the highest specific activity of the enzyme was found in the soluble fraction.
摘要
已发现超氧化物歧化酶广泛分布于所检测的人脑中的所有区域，且比活性大致相同。在亨廷顿舞蹈病的基底神经节变性过程中，其活性并未降低。对人和豚鼠大脑皮层进行亚细胞分级分离后，发现该酶在可溶部分的比活性最高。
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