Kennedy D S, Linden G J
Division of Restorative Dentistry, School of Dentistry, Queen's University, Belfast.
J Ir Dent Assoc. 2000;46(1):3-4.
Gingival overgrowth is a well documented and common side-effect of cyclosporin therapy. Gingival swelling in this condition hinders efficient oral hygiene and is of aesthetic concern to patients. This case report outlines rapid and dramatic reduction in overgrowth when tacrolimus replaced cyclosporin as the immunosuppressive agent in a renal transplant patient with established overgrowth.
牙龈增生是环孢素治疗中一种有充分文献记载的常见副作用。在这种情况下，牙龈肿胀会妨碍有效的口腔卫生，并且是患者关注的美观问题。本病例报告概述了一名已出现牙龈增生的肾移植患者，当他克莫司取代环孢素作为免疫抑制剂时，牙龈增生迅速且显著减轻。
