Rho J R, Oh M S, Jang K H, Cho K W, Shin J
Marine Natural Products Laboratory, Korea Ocean Research & Development Institute, Ansan P.O. Box 29, Seoul 425-600 Korea.
J Nat Prod. 2001 Apr;64(4):540-3. doi: 10.1021/np0005154.
Eight diterpenes and norditerpenes including five new xenicane metabolites (4--8) have been isolated from the gorgonian Acalycigorgia inermis. The structures of these compounds have been determined by combined spectroscopic analysis. The new compounds exhibited significant cytotoxicity against a human leukemia cell-line.
从无刺柳珊瑚Acalycigorgia inermis中分离出8种二萜和去甲二萜，其中包括5种新的异海松烷类代谢产物（4 - 8）。这些化合物的结构已通过光谱分析联用技术确定。新化合物对一种人类白血病细胞系表现出显著的细胞毒性。
