Sung P J, Su J H, Wang G H, Lin S F, Duh C Y, Sheu J H
Department of Marine Resources, National Sun Yat-Sen University, Kaohsiung, Taiwan 804, Republic of China.
J Nat Prod. 1999 Mar;62(3):457-63. doi: 10.1021/np980446h.
Eight new briarane-type diterpenes, excavatolides F-M (1-8), have been isolated from the gorgonian Briareum excavatum. The structures and relative stereochemistry of these compounds were established by spectral analysis and chemical methods. The cytotoxicity of these compounds toward various cancer cell lines has also been determined.
从柳珊瑚Briareum excavatum中分离出了8种新的刺柏烷型二萜类化合物，即excavatolides F-M（1-8）。通过光谱分析和化学方法确定了这些化合物的结构和相对立体化学。还测定了这些化合物对各种癌细胞系的细胞毒性。
