Halaby T, Boots H, Vermeulen A, van der Ven A, Beguin H, van Hooff H, Jacobs J
Departments of Medical Microbiology, Maastricht University Hospital, 6202 AZ, Maastricht, The Netherlands.
J Clin Microbiol. 2001 May;39(5):1952-5. doi: 10.1128/JCM.39.5.1952-1955.2001.
We report on a case of phaeohyphomycosis caused by Alternaria infectoria in a renal transplant recipient with pulmonary infiltrates and multiple skin lesions. Diagnosis was based on microscopy and culture of the skin lesions. Treatment consisted of a combination of surgical excision and systemic antifungal therapy, first with itraconazole and subsequently with liposomal amphotericin B, for 39 days. At a 20-month follow-up visit, no recurrence of the skin lesions or the pulmonary infiltrates had occurred.
我们报告了一例由链格孢菌引起的暗色丝孢霉病,患者为肾移植受者,有肺部浸润和多处皮肤病变。诊断基于皮肤病变的显微镜检查和培养。治疗包括手术切除和全身抗真菌治疗相结合,首先使用伊曲康唑,随后使用脂质体两性霉素B,持续39天。在20个月的随访中,皮肤病变和肺部浸润均未复发。