Rothenberg S S, Partrick D A, Bealer J F, Chang J H
Departments of Pediatric Surgery, Hospital for Infants and Children, Presbyterian/St Luke's Medical Center and The Children's Hospital, University of Colorado, Denver, CO, USA.
J Pediatr Surg. 2001 May;36(5):808-10. doi: 10.1053/jpsu.2001.22967.
Achalasia is an uncommon disease in children, but when present can result in severe disabling symptoms often requiring surgical intervention. This report describes the authors' experience with thoracoscopic (TH) and later laparoscopic Heller (LH) myotomy for definitive treatment of this disease.
Nine patients with achalasia were referred for surgical therapy. Ages ranged from 5 to 17 years and weight from 23 to 78 kg. All had undergone at least one dilatation with recurrence of symptoms. The first 4 were treated by TH and the last five by LH. The 5 LH procedures also included a partial fundoplication.
All procedures were completed successfully using minimally invasive techniques. Operating times averaged 95 minutes for TH and 62 minutes for LH. One patient undergoing TH had a small esophageal perforation repaired primarily. The other 3 TH patients were started on clear liquids within 1 day and discharged on day 2. One patient had recurrent symptoms at 6 months and underwent a LH for an incomplete TH. All 5 LH patients were discharged on postoperative day 1. One had an esophageal perforation 4 days after operation requiring laparoscopic repair. Seven of 9 patients are asymptomatic. Studies of pH levels in 2 asymptomatic TH patients show mild gastroesophageal reflux (GER).
Minimally invasive Heller myotomy is a safe and effective procedure in children. TH results in a slightly longer operating time and hospital stay and, without a partial fundoplication, also may be associated with a higher incidence of silent GER. From these results, we prefer LH with a Dor fundoplication for treatment of achalasia in children.
贲门失弛缓症在儿童中并不常见,但一旦出现,可导致严重的致残症状,常需手术干预。本报告描述了作者使用胸腔镜(TH)和后来的腹腔镜Heller(LH)肌切开术对该疾病进行确定性治疗的经验。
9例贲门失弛缓症患者被转诊接受手术治疗。年龄从5岁到17岁不等,体重从23公斤到78公斤。所有患者均至少接受过一次扩张治疗,但症状复发。前4例采用TH治疗,后5例采用LH治疗。5例LH手术还包括部分胃底折叠术。
所有手术均使用微创技术成功完成。TH手术平均时间为95分钟,LH手术平均时间为62分钟。1例接受TH手术的患者出现小的食管穿孔,主要进行了修补。其他3例TH手术患者术后1天开始进清流食,第2天出院。1例患者在6个月时症状复发,因TH手术不完全而接受LH手术。所有5例LH手术患者术后第1天出院。1例患者术后4天出现食管穿孔,需要腹腔镜修补。9例患者中有7例无症状。对2例无症状TH手术患者的pH值水平研究显示有轻度胃食管反流(GER)。
微创Heller肌切开术在儿童中是一种安全有效的手术方法。TH手术导致手术时间和住院时间略长,并且在没有部分胃底折叠术的情况下,也可能与无症状GER的发生率较高有关。根据这些结果,我们更倾向于使用Dor胃底折叠术的LH手术来治疗儿童贲门失弛缓症。