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胸腔镜与腹腔镜下贲门失弛缓症Heller肌切开术的比较

Comparison of thoracoscopic and laparoscopic Heller myotomy for achalasia.

作者信息

Patti M G, Arcerito M, De Pinto M, Feo C V, Tong J, Gantert W, Way L W

机构信息

Department of Surgery, University of California, San Francisco, San Francisco, California 94143-0788, USA.

出版信息

J Gastrointest Surg. 1998 Nov-Dec;2(6):561-6. doi: 10.1016/s1091-255x(98)80057-7.

Abstract

For more than three decades experts have debated the relative merits of thoracoscopic Heller myotomy (no antireflux procedure) vs. laparoscopic Heller myotomy plus Dor fundoplication for treatment of achalasia. The aim of this study was to compare the results of these two methods with respect to (1) relief of dysphagia, (2) incidence of postoperative gastroesophageal reflux, and (3) hospital course. Sixty patients with esophageal achalasia were operated on between 1991 and 1996. Thirty underwent a thoracoscopic Heller myotomy and 30 had a laparoscopic Heller myotomy with a Dor fundoplication. The two groups were similar with respect to demographic characteristics, clinical findings, and extent of manometric abnormalities. Preoperative pH monitoring showed abnormal reflux in two patients in the laparoscopic group. Average hospital stay was 84 hours for the thoracoscopic group and 42 hours for the laparoscopic group. Excellent (no dysphagia) or good (dysphagia less than once a week) results were obtained in 87% of patients in the thoracoscopic group and in 90% of patients in the laparoscopic group. Postoperative pH monitoring showed abnormal reflux in 6 (60%) of 10 patients in the thoracoscopic group and in 1 (10%) of 10 patients in the laparoscopic group. The two patients in the laparoscopic group who had reflux preoperatively had normal reflux scores postoperatively. Laparoscopic Heller myotomy with Dor fundoplication was found to be superior to thoracoscopic Heller myotomy. Both operations relieved dysphagia, but the laparoscopic approach avoided postoperative reflux and even corrected reflux present preoperatively. In addition, the patients were more comfortable and left the hospital earlier following a laparoscopic myotomy. Whether it is truly possible to perform a Heller myotomy without an antireflux procedure in a way that relieves dysphagia and regularly avoids reflux remains questionable.

摘要

三十多年来,专家们一直在争论胸腔镜下Heller肌切开术(不进行抗反流手术)与腹腔镜下Heller肌切开术加Dor胃底折叠术治疗贲门失弛缓症的相对优点。本研究的目的是比较这两种方法在以下方面的结果:(1)吞咽困难的缓解情况;(2)术后胃食管反流的发生率;(3)住院过程。1991年至1996年间,对60例食管贲门失弛缓症患者进行了手术。30例行胸腔镜下Heller肌切开术,30例行腹腔镜下Heller肌切开术加Dor胃底折叠术。两组在人口统计学特征、临床表现和测压异常程度方面相似。术前pH监测显示腹腔镜组有2例患者存在异常反流。胸腔镜组的平均住院时间为84小时,腹腔镜组为42小时。胸腔镜组87%的患者和腹腔镜组90%的患者获得了优秀(无吞咽困难)或良好(吞咽困难每周少于一次)的结果。术后pH监测显示,胸腔镜组10例患者中有6例(60%)出现异常反流,腹腔镜组10例患者中有1例(10%)出现异常反流。腹腔镜组术前有反流的2例患者术后反流评分正常。发现腹腔镜下Heller肌切开术加Dor胃底折叠术优于胸腔镜下Heller肌切开术。两种手术都缓解了吞咽困难,但腹腔镜手术避免了术后反流,甚至纠正了术前存在的反流。此外,腹腔镜肌切开术后患者感觉更舒适,出院更早。不进行抗反流手术而以缓解吞咽困难并定期避免反流的方式进行Heller肌切开术是否真的可行仍存在疑问。

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