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静脉淤滞综合征和静脉溃疡发病率的趋势:一项基于人群的25年研究。

Trends in the incidence of venous stasis syndrome and venous ulcer: a 25-year population-based study.

作者信息

Heit J A, Rooke T W, Silverstein M D, Mohr D N, Lohse C M, Petterson T M, O'Fallon W M, Melton L J

机构信息

Division of Cardiovascular Diseases, Section of Vascular Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA.

出版信息

J Vasc Surg. 2001 May;33(5):1022-7. doi: 10.1067/mva.2001.113308.

Abstract

BACKGROUND

The incidence rates of venous stasis syndrome and venous ulcer are uncertain, and trends in incidence are unknown.

METHODS

We performed a retrospective review of the complete (inpatient and outpatient) medical records of a community population (Olmsted County, Minnesota) to estimate the incidence of venous stasis syndrome and venous ulcer during the 25-year period, 1966 to 1990, and to describe trends in incidence.

RESULTS

A total of 1131 patients received a first lifetime diagnosis of venous stasis syndrome. A total of 263 patients received a first lifetime diagnosis of venous ulcer. The overall incidence of venous stasis syndrome and venous ulcer were 76.1 and 18.0 per 100,000 person-years, respectively. The incidence of both was higher in women than in men (83.7 vs 67.4 per 100,000 person-years for venous stasis syndrome; 20.4 vs 14.6 per 100,000 for venous ulcer) and increased with age for both sexes. There was no clear trend in the incidence of venous stasis syndrome over the 25-year period. Compared with 1966 to 1970, the incidence of venous ulcer decreased in 1971 to 1980, but was unchanged after 1981. Among 945 patients with venous stasis only, 60 subsequently had a venous ulcer. The average (+/- SD) time from venous stasis diagnosis to development of a venous ulcer was 5.0 (+/- 5.0) years.

CONCLUSION

Venous stasis syndrome and venous ulcer are common, especially in the elderly population. The incidence of venous stasis syndrome has not changed since 1966, and venous ulcer incidence is unchanged since 1981. More accurate identification of patients at risk for venous stasis syndrome and venous ulcer and more effective prevention are needed.

摘要

背景

静脉淤滞综合征和静脉溃疡的发病率尚不确定,且发病率趋势未知。

方法

我们对明尼苏达州奥姆斯特德县社区人群的完整(住院和门诊)病历进行了回顾性研究,以估计1966年至1990年这25年间静脉淤滞综合征和静脉溃疡的发病率,并描述发病率趋势。

结果

共有1131例患者首次被诊断为静脉淤滞综合征。共有263例患者首次被诊断为静脉溃疡。静脉淤滞综合征和静脉溃疡的总体发病率分别为每10万人年76.1例和18.0例。两者在女性中的发病率均高于男性(静脉淤滞综合征为每10万人年83.7例对67.4例;静脉溃疡为每10万人年20.4例对14.6例),且男女发病率均随年龄增长而增加。在这25年期间,静脉淤滞综合征的发病率没有明显趋势。与1966年至1970年相比,1971年至1980年静脉溃疡的发病率有所下降,但1981年后保持不变。在仅患有静脉淤滞的945例患者中,有60例随后发生了静脉溃疡。从静脉淤滞诊断到发生静脉溃疡的平均(±标准差)时间为5.0(±5.0)年。

结论

静脉淤滞综合征和静脉溃疡很常见,尤其是在老年人群中。自1966年以来静脉淤滞综合征的发病率没有变化,自1981年以来静脉溃疡的发病率也没有变化。需要更准确地识别静脉淤滞综合征和静脉溃疡的高危患者,并采取更有效的预防措施。

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