de Castro Alex Carlos Ferreira, Barbosa Anderson Veiga, Lima David Fonseca, Vidal João Vitor Rodrigues, Reis José Maciel Caldas, Carneiro Saul Rassy
Universidade Federal do Pará UFPA, Belém, PA, Brasil.
Universidade do Estado do Pará UEPA, Belém, PA, Brasil.
J Vasc Bras. 2025 Jul 28;24:e20250006. doi: 10.1590/1677-5449.202500062. eCollection 2025.
The systematic review with meta-analysis aimed to investigate the occurrence of Chronic Venous Insufficiency (CVI) in patients with Type II Diabetes Mellitus (T2DM). The guiding research question was structured using the PECOT framework (P: population; E: exposure; C: comparison; O: outcome; T: type of study), and the risk of bias was assessed using the ROBIS-I tool. A total of four studies were included in the analysis. The findings revealed that the prevalence of CVI in patients with T2DM was 55%, with a prevalence ratio of 1.51 (95% CI: 1.01 to 2.26). These results suggest that individuals with T2DM have a significantly higher prevalence of CVI compared to those without the condition. However, the review identified several limitations, such as the scarcity of longitudinal studies and variability in the diagnostic criteria for CVI among the included studies. The authors conclude that further research is warranted to address these gaps and deepen understanding of the relationship between T2DM and CVI.
这项带有荟萃分析的系统评价旨在调查2型糖尿病（T2DM）患者中慢性静脉功能不全（CVI）的发生率。指导性研究问题是使用PECOT框架构建的（P：人群；E：暴露因素；C：对照；O：结局；T：研究类型），并使用ROBIS-I工具评估偏倚风险。分析共纳入四项研究。研究结果显示，T2DM患者中CVI的患病率为55%，患病率比值为1.51（95%CI：1.01至2.26）。这些结果表明，与未患该病的个体相比，T2DM患者CVI的患病率显著更高。然而，该评价发现了几个局限性，例如纵向研究的稀缺以及纳入研究中CVI诊断标准的变异性。作者得出结论，有必要进行进一步研究以填补这些空白，并加深对T2DM与CVI之间关系的理解。
