Systematic review and meta-analysis of the impact of diabetes mellitus on chronic venous insufficiency.

The systematic review with meta-analysis aimed to investigate the occurrence of Chronic Venous Insufficiency (CVI) in patients with Type II Diabetes Mellitus (T2DM). The guiding research question was structured using the PECOT framework (P: population; E: exposure; C: comparison; O: outcome; T: type of study), and the risk of bias was assessed using the ROBIS-I tool. A total of four studies were included in the analysis. The findings revealed that the prevalence of CVI in patients with T2DM was 55%, with a prevalence ratio of 1.51 (95% CI: 1.01 to 2.26). These results suggest that individuals with T2DM have a significantly higher prevalence of CVI compared to those without the condition. However, the review identified several limitations, such as the scarcity of longitudinal studies and variability in the diagnostic criteria for CVI among the included studies. The authors conclude that further research is warranted to address these gaps and deepen understanding of the relationship between T2DM and CVI.