Lee D H, Sohn H W, Park S H, Kang Y K
Department of Ophthalmology and Anatomic Pathology, Ilsan Paik Hospital, Ilsan, Korea.
Cornea. 2001 May;20(4):427-9. doi: 10.1097/00003226-200105000-00019.
This report aimed to discuss two nearly identical cases of primary conjunctival mucosa-associated lymphoid tissue (MALT) lymphoma mimicking allergic conjunctivitis.
Two patients were referred for intractability to conventional treatment of initial diagnoses of allergic conjunctivitis. On ocular examination, normally pigmented, giant papilla-like lesions were found bilaterally in the upper conjunctiva. Excisional biopsies were performed.
Histopathologic and immunohistochemical examination of the conjunctival biopsies indicated MALT lymphoma in both patients. The patients subsequently received radiation therapy and achieved complete remission with no evidence of recurrence during follow-up periods of 13 and 11 months.
Conjunctival low-grade lymphoma may share similar clinical features with allergic conjunctivitis. Ophthalmologists should be concerned that primary conjunctival low-grade malignant lymphoma can be misdiagnosed as allergic conjunctivitis
本报告旨在探讨两例几乎相同的原发性结膜黏膜相关淋巴组织（MALT）淋巴瘤，其表现类似过敏性结膜炎。
两名患者因最初诊断为过敏性结膜炎但常规治疗无效而前来就诊。眼部检查发现双侧上结膜有正常色素沉着的巨大乳头样病变。进行了切除活检。
结膜活检的组织病理学和免疫组织化学检查表明两名患者均为MALT淋巴瘤。两名患者随后接受了放射治疗，并在13个月和11个月的随访期内实现了完全缓解，无复发迹象。
结膜低度淋巴瘤可能与过敏性结膜炎具有相似的临床特征。眼科医生应注意原发性结膜低度恶性淋巴瘤可能被误诊为过敏性结膜炎。
