van Kappel A L, Martínez-García C, Elmståhl S, Steghens J P, Chajès V, Bianchini F, Kaaks R, Riboli E
Unit of Nutrition and Cancer, International Agency for Research on Cancer, 150 cours Albert-Thomas, 69372 Lyon, France.
Int J Vitam Nutr Res. 2001 Mar;71(2):97-102. doi: 10.1024/0300-9831.71.2.97.
We conducted a cross-sectional pilot study on healthy pre-menopausal women (aged 45-50 years) living in Granada, in the south of Spain (n = 39) and Malmö, in the south of Sweden (n = 38) in order to compare their plasma carotenoid levels and to investigate the relationship between the differences in food consumption. Plasma concentrations of six carotenoids were measured using high performance liquid chromatography, habitual diet (at individual level) was estimated by food frequency questionnaires and 24-hour diet recalls were used for standardised measurement of diet at group-level. We found that women in Granada consumed more fruit and vegetables than women in Malmö. Plasma concentrations of beta-cryptoxanthin, lycopene, zeaxanthin, total carotenoids and alpha-tocopherol were higher in Granada than in Malmö, although plasma concentrations of alpha-carotene and retinol were higher in Malmö. Both within and between study centres, consumption of fruit and vegetables correlated positively with plasma concentrations of different carotenoids. The study showed that differences in consumption of fruit and vegetables between the two European centres were reflected in plasma carotenoid concentrations.
我们对居住在西班牙南部格拉纳达（45 - 50岁的健康绝经前女性，n = 39）和瑞典南部马尔默（n = 38）的女性进行了一项横断面试点研究，以比较她们的血浆类胡萝卜素水平，并调查食物消费差异之间的关系。使用高效液相色谱法测量六种类胡萝卜素的血浆浓度，通过食物频率问卷估计习惯性饮食（个体水平），并使用24小时饮食回忆法对组水平的饮食进行标准化测量。我们发现，格拉纳达的女性比马尔默的女性摄入更多的水果和蔬菜。格拉纳达的β-隐黄质、番茄红素、玉米黄质、总类胡萝卜素和α-生育酚的血浆浓度高于马尔默，尽管马尔默的α-胡萝卜素和视黄醇的血浆浓度更高。在研究中心内部和之间，水果和蔬菜的消费与不同类胡萝卜素的血浆浓度呈正相关。该研究表明，这两个欧洲中心之间水果和蔬菜消费的差异反映在血浆类胡萝卜素浓度上。
