Saxena S, Jalali S, Meredith T A, Holekamp N M, Kumar D
Department of Ophthalmology and Visual Sciences, King George's Medical College, University of Lucknow, Lucknow, India.
Indian J Ophthalmol. 2000 Dec;48(4):321-30.
Diabetic retinopathy remains a major cause of blindness despite increased understanding of this disease and identification of successful treatments. The Diabetic Retinopathy Study identified risk factors associated with a high risk of blindness and confirmed the benefits of panretinal photocoagulation. The Early Treatment Diabetic Retinopathy Study defined the retinal characteristics, indications of treatment and results of laser treatment of clinically significant macular oedema. The Diabetic Retinopathy Vitrectomy study established the benefits and timing of vitrectomy for non-clearing vitreous haemorrhage and severe proliferative diabetic retinopathy. The Diabetes Control and Complications Trial and the United Kingdom Prospective Diabetes Study have also demonstrated the value of tight control of blood sugar and blood pressure in diabetic retinopathy. These studies developed specific recommendations for the management of diabetic retinopathy. Optimum use of this information can minimize visual loss due to diabetic retinopathy.
尽管对糖尿病视网膜病变的认识有所提高，且已确定了成功的治疗方法，但它仍然是导致失明的主要原因。糖尿病视网膜病变研究确定了与高失明风险相关的危险因素，并证实了全视网膜光凝的益处。早期治疗糖尿病视网膜病变研究明确了临床上显著黄斑水肿的视网膜特征、治疗指征及激光治疗效果。糖尿病视网膜病变玻璃体切除术研究确定了针对不吸收的玻璃体出血和严重增殖性糖尿病视网膜病变进行玻璃体切除术的益处及时机。糖尿病控制与并发症试验以及英国前瞻性糖尿病研究也证明了严格控制血糖和血压在糖尿病视网膜病变中的价值。这些研究为糖尿病视网膜病变的管理制定了具体建议。最佳利用这些信息可将糖尿病视网膜病变导致的视力丧失降至最低。
