Málek F, Karel I, Polásek R, Spacek R, Lisa L, Dvorák J, Stanka P
Kardiologické oddĕlení I. interní kliniky Fakultní nemocnice Královské Vinohrady a 3. lékarské fakulty Univerzity Karlovy, Praha.
Vnitr Lek. 2000 Oct;46(10):693-6.
The authors assessed serum copper and lipoprotein concentrations in a group of 67 patients hospitalized successively at the cardiological department. During hospitalization they were subjected to selective coronarography with assessment of the angiographic score. In 35 patients the angiographic examination was made during the chronic stage of IHD (group A), in 32 patients it was indicated on account of acute coronary syndrome (group B). The authors found that serum copper concentrations are significantly higher in patients with acute forms of IHD (group B, p < 0.001). Serum copper concentrations do not correlate significantly with lipoprotein concentrations nor with the extent of coronary atheroclerosis (angiographic score).
作者评估了67名先后入住心脏病科的患者的血清铜和脂蛋白浓度。在住院期间，他们接受了选择性冠状动脉造影，并评估了血管造影评分。35例患者在缺血性心脏病（IHD）慢性期进行了血管造影检查（A组），32例患者因急性冠状动脉综合征进行了血管造影检查（B组）。作者发现，IHD急性形式患者（B组，p<0.001）的血清铜浓度显著更高。血清铜浓度与脂蛋白浓度以及冠状动脉粥样硬化程度（血管造影评分）均无显著相关性。
