孕期梅毒控制：一项分权式项目的有效性与可持续性
Syphilis control during pregnancy: effectiveness and sustainability of a decentralized program.
作者信息
Fonck K, Claeys P, Bashir F, Bwayo J, Fransen L, Temmerman M
机构信息
International Center for Reproductive Health, Ghent University, UZ P3, De Pintelaan, 9000 Ghent, Belgium.
出版信息
Am J Public Health. 2001 May;91(5):705-7. doi: 10.2105/ajph.91.5.705.
Abstract
OBJECTIVES
This study sought to assess the performance, effectiveness, and costs of a decentralized antenatal syphilis screening program in Nairobi, Kenya.
METHODS
Health clinic data, quality control data, and costs were analyzed.
RESULTS
The rapid plasma reagin (RPR) seroprevalence was 3.4%. In terms of screening, treatment, and partner notification, the program's performance was adequate. The program's effectiveness was problematic because of false-negative and false-positive RPR results. The cost per averted case was calculated to be US$95 to US$112.
CONCLUSIONS
The sustainability of this labor-intensive program is threatened by costs and logistic constraints. Alternative strategies, such as the mass epidemiologic treatment of pregnant women in high-prevalence areas, should be considered.
摘要
目的
本研究旨在评估肯尼亚内罗毕一项分散式产前梅毒筛查项目的性能、效果和成本。
方法
对健康诊所数据、质量控制数据和成本进行了分析。
结果
快速血浆反应素（RPR）血清阳性率为3.4%。在筛查、治疗和性伴侣通知方面，该项目的表现尚可。由于RPR结果出现假阴性和假阳性，该项目的效果存在问题。计算得出避免一例梅毒感染的成本为95美元至112美元。
结论
这个劳动密集型项目的可持续性受到成本和后勤限制的威胁。应考虑其他策略，如在高流行地区对孕妇进行大规模流行病学治疗。
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