Valentik M F, Tov N L
Ter Arkh. 1986;58(8):101-2.
The authors presented the results of a clinical study of an atypical course of secondary renal amyloidosis developing in a patient with pulmonary tuberculosis and progressing against a background of chronic post-tuberculosis bronchitis. The disease manifested itself in the acute development of the nephrotic syndrome which could be arrested as a result of tuberculostatic therapy. Clinico-laboratory signs of the disease were absent for 20 yrs., then arterial hypertension and chronic renal failure accompanied by minimum proteinuria, developed. The diagnosis of renal amyloidosis was confirmed by nephrobiopsy. Considerable difficulties arose in differential diagnosis with glomerulonephritis in such a clinical course.
作者介绍了一名肺结核患者继发肾淀粉样变性的非典型病程的临床研究结果,该病程在慢性肺结核后支气管炎背景下进展。该疾病表现为肾病综合征的急性发作,抗结核治疗后病情得以缓解。20年来一直没有该疾病的临床实验室体征,随后出现动脉高血压和慢性肾衰竭,并伴有微量蛋白尿。肾活检证实了肾淀粉样变性的诊断。在这样的临床病程中,与肾小球肾炎的鉴别诊断存在相当大的困难。