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[Embryonal rhabdomyosarcoma of the prostate. Report of a case and review of the literature].

作者信息

Segura Huerta A, López Tendero P, Yuste Izquierdo A, Gironés Sarrió R, Pérez Fidalgo J, Aparicio Urtasun J

机构信息

Servicio de Oncología Médica, Hospital Universitario La Fe, Valencia.

出版信息

Actas Urol Esp. 2001 Feb;25(2):144-9. doi: 10.1016/s0210-4806(01)72590-9.

DOI:10.1016/s0210-4806(01)72590-9
PMID:11345801
Abstract

The rhabdomyosarcoma (RMS) is a tumour derived from the mesenchymal cells that give origin to striate muscle. It appears most frequently at the pediatric age, although some appear in adolescence and in young adulthood. It is a high grade malignancy that metastatisis frequently (most importantly to the lung). There are two principal types: alveolar RMS and embrionary RMS. It can appear in any localization, being the most frequent the periorbitary area and the paranasal sinuses, and the second in frequency the genitourinary system (bladder, prostate and vagina). The therapeutic management is multidisciplinary and local therapies must always be accompanied with polychemotherapy. With combined treatments a curation rate of almost 90% can be reached in good prognosis cases, although it drops to 20% in those with disfavourable prognostic factors. The protocols with higher chemotherapy doses and subsequent rescue with blood-borne progenitor cells have not yet proved their efficiency. We present the case of a fifteen-year old patient with an embrionary rhabdomyosarcoma of the prostate, we analyze the clinical evolution and we revise the present therapeutic management of these neoplasies.

摘要

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