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口臭患者的特征及气相色谱法在口臭诊断中的应用价值

Characteristics of patients complaining of halitosis and the usefulness of gas chromatography for diagnosing halitosis.

作者信息

Oho T, Yoshida Y, Shimazaki Y, Yamashita Y, Koga T

机构信息

Department of Preventive Dentistry, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 May;91(5):531-4. doi: 10.1067/moe.2001.112543.

Abstract

OBJECTIVE

The purpose of this study was to examine the characteristics of patients complaining of halitosis and to evaluate the diagnostic accuracy of 3 methods of measuring halitosis.

STUDY DESIGN

The actual degree of halitosis was determined through use of an organoleptic test in 155 patients aged 46 +/- 17 years (mean +/- SD). The volatile sulfur compounds (VSCs) were determined with gas chromatography and with sulfide monitoring.

RESULTS

The organoleptic test revealed that 55% of the subjects had either no mouth odor or slight mouth odor. There was a significant correlation between the organoleptic score and the total VSC level as determined through use of other methods. The critical discrimination value of the total VSC level was calculated to be 0.057 ppm for gas chromatography and 0.117 ppm for sulfide monitoring; high sensitivity and specificity were obtained when the gas chromatography value was used. The amount of tongue coating was significantly greater in the halitosis-positive group than in the halitosis-negative group, whereas there was no difference in salivary flow rate between the 2 groups.

CONCLUSION

These results indicate that determining VSCs with gas chromatography is a useful means of diagnosing halitosis.

摘要

目的

本研究旨在探讨主诉口臭患者的特征,并评估三种口臭测量方法的诊断准确性。

研究设计

通过感官测试确定了155名年龄为46±17岁(均值±标准差)患者的实际口臭程度。采用气相色谱法和硫化物监测法测定挥发性硫化物(VSCs)。

结果

感官测试显示,55%的受试者无口臭或有轻微口臭。感官评分与通过其他方法测定的总VSC水平之间存在显著相关性。气相色谱法测定的总VSC水平的临界判别值计算为0.057 ppm(百万分之一),硫化物监测法为0.117 ppm;使用气相色谱法测定值时可获得高灵敏度和特异性。口臭阳性组的舌苔量显著高于口臭阴性组,而两组间唾液流速无差异。

结论

这些结果表明,气相色谱法测定VSCs是诊断口臭的一种有用方法。

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