Brown Zora Kramer
Breast Cancer Resource Committee, Washington, DC.
Breast J. 2000 Oct;6(5):288-290. doi: 10.1046/j.1524-4741.2000.20045.x.
In this presentation, I share my experiences as a fourth generation breast cancer survivor and, subsequently, as an ardent advocate of breast cancer issues. My presentation is informed, in great part, by the experiences of my great-grandmother, grandmother, mother, and three sisters, all of whom suffered the ravages of breast cancer. It is informed, in even greater part, by my own bout with breast cancer with which I was initially diagnosed at the age of thirty-two. Despite two separate mastectomies, I have survived the disease for more than nineteen years. This presentation, therefore, identifies issues associated with a genetic predisposition to breast cancer, highlights the particular vulnerability of African American women, and advocates awareness and education as a key to breast cancer survivorship. Genetic predisposition to breast cancer dictates precautions of which women of all races and nationalities must be aware. This presentation utilizes the most recent data in identifying and assessing the efficacy of those precautions, including mammography, self-breast examination, diet, drug therapy, and surgery. It also reviews the role of scientific studies and clinical trials in the prevention, diagnosis, and treatment of breast cancer. Developments in genetic mapping are particularly promising. My broad experience with breast cancer led to my founding the Breast Cancer Resource Committee, a non-profit organization that has as its purpose the provision of education initiatives and support, particularly for African American women, who bear an unequal burden in the war against breast cancer. While breast cancer is the second leading cause of cancer death among all women, it is the leading cause of cancer death among African American women. Although awareness and early precautions do not necessarily prevent breast cancer, they remain central to breast cancer survivorship. My own family history, as well as the 1.3 million breast cancer survivors in my country, documents this reality.
在本次演讲中，我将分享自己作为第四代乳腺癌幸存者的经历，以及随后作为乳腺癌问题热情倡导者的经历。我的演讲很大程度上受到了我的曾祖母、祖母、母亲和三个姐妹经历的影响，她们都遭受了乳腺癌的折磨。更大程度上，它受到了我自己与乳腺癌抗争经历的影响，我最初在32岁时被诊断出患有乳腺癌。尽管经历了两次乳房切除术，我还是从这种疾病中存活了19年多。因此，本次演讲将识别与乳腺癌遗传易感性相关的问题，强调非裔美国女性的特殊脆弱性，并倡导提高认识和开展教育是乳腺癌幸存者的关键。乳腺癌的遗传易感性决定了所有种族和国籍的女性都必须了解的预防措施。本次演讲利用最新数据来识别和评估这些预防措施的有效性，包括乳房X光检查、自我乳房检查、饮食、药物治疗和手术。它还回顾了科学研究和临床试验在乳腺癌预防、诊断和治疗中的作用。基因图谱绘制方面的进展尤其令人期待。我在乳腺癌方面的广泛经历促使我成立了乳腺癌资源委员会，这是一个非营利组织，其宗旨是提供教育倡议和支持，特别是为在抗击乳腺癌的斗争中承担不平等负担的非裔美国女性。虽然乳腺癌是所有女性中癌症死亡的第二大主要原因，但它是非裔美国女性中癌症死亡的首要原因。尽管提高认识和早期预防不一定能预防乳腺癌，但它们仍然是乳腺癌幸存者的核心。我自己的家族病史，以及我国130万乳腺癌幸存者，都证明了这一现实。
