Bockholdt B, Klug E, Schneider V
Institute of Legal Medicine, UK Benjamin Franklin, Free University, Hittorfstr. 18, D-14195, Berlin, Germany.
Forensic Sci Int. 2001 Jun 1;119(1):138-40. doi: 10.1016/s0379-0738(00)00393-5.
Doxylamine is an antihistamine of the ethanolamine class. It is used primarily as a sleep-inducing agent. Only a few reports can be found in the literature about lethal intoxications with doxylamine, but many with combined intoxications. Doxylamine is, aside from diphenhydramine, the only chemically defined active ingredient in some sleeping medications which is available without a prescription in the Federal Republic of Germany. Two cases of doxylamine poisoning are presented, in which high doxylamine concentrations were found in the blood and organs.
多西拉敏是一种乙醇胺类抗组胺药。它主要用作诱导睡眠的药物。关于多西拉敏致死性中毒的文献报道较少,但合并中毒的报道较多。除苯海拉明外,多西拉敏是德意志联邦共和国一些无需处方即可获得的睡眠药物中唯一化学性质明确的活性成分。本文介绍了两例多西拉敏中毒病例,在血液和器官中发现了高浓度的多西拉敏。