Kabukcuoglu F, Sungun A, Sentürk B A, Evren I, Ilhan R
Sisli Etfal Training and Research Hospital, Pathology Department, Istanbul, Turkey.
Pathol Oncol Res. 2001;7(1):60-2. doi: 10.1007/BF03032607.
Germ cell tumors constitute a very complicated group of tumors of the ovary and their histogenesis is not yet clarified. Besides their histological heterogeneity, sarcomatous areas have also been described. A right ovarian mass was found in a 23-year-old female, who was being treated in the hospital for miscarriage. Disseminated omental metastases were detected during abdominal laparotomy. Pathological examination of the dissected material revealed the tumor to be a mixed germ cell tumor (immature teratoma and dysgerminoma) with sarcomatous component. Areas resembling granulosa cell tumor were also encountered. This ovarian tumor with many different histopathological features is presented with a review of the literature. The importance of thorough sampling in determining the type and extent of the malignant components is also emphasized due to their direct relation with the prognosis.
生殖细胞肿瘤是一组非常复杂的卵巢肿瘤,其组织发生尚未阐明。除了组织学异质性外,还描述了肉瘤样区域。一名23岁女性因流产在医院接受治疗时发现右侧卵巢肿物。剖腹探查时发现广泛的网膜转移。对切除标本的病理检查显示该肿瘤为混合性生殖细胞肿瘤(未成熟畸胎瘤和无性细胞瘤),伴有肉瘤样成分。还发现了类似颗粒细胞瘤的区域。本文结合文献复习介绍了这种具有多种不同组织病理学特征的卵巢肿瘤。由于恶性成分的类型和范围与预后直接相关,因此强调了全面取材在确定其类型和范围方面的重要性。