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耐甲氧西林葡萄球菌日益严重的问题——印度的情况

Growing problem of methicillin resistant staphylococci--Indian scenario.

作者信息

Verma S, Joshi S, Chitnis V, Hemwani N, Chitnis D

机构信息

Deptt. of Microbiology and Immunology, Choithram Hospital & Research Centre, Indore, Pin-452001.

出版信息

Indian J Med Sci. 2000 Dec;54(12):535-40.

Abstract

In the present study MRSA prevalence increased from 12% in 1992 to 80.83% in 1999. Indian literature shows that MRSA incidence was as low as 6.9% in 1988 and reached to 24% and 32.6% in Vellore and Lucknow in 1994 and was of the same order in Mumbai, Delhi and Bangalore in 1996 and in Rohtak and Mangalore in 1999. However, in some of the centres it was as high as 87%. All the MRSA isolates in India including in the present study were sensitive to vancomycin and resistance to netilmycin appears to be low among MRSA isolates in India. All the MRSA isolates were also found to be sensitive to teicoplanin in the present study. Like in other Indian studies, resistance to cotrimoxazole, erythromycin, gentamicin, other penicillins and cephalosporins appeared to be a common feature for MRSA isolates in the present study.

摘要

在本研究中,耐甲氧西林金黄色葡萄球菌(MRSA)的流行率从1992年的12%上升至1999年的80.83%。印度文献表明,1988年MRSA的发病率低至6.9%,1994年在韦洛尔和勒克瑙分别升至24%和32.6%,1996年在孟买、德里和班加罗尔以及1999年在罗塔克和芒格洛尔的发病率处于同一水平。然而,在一些中心该发病率高达87%。包括本研究在内,印度所有的MRSA分离株对万古霉素敏感,且印度MRSA分离株对奈替米星的耐药性似乎较低。在本研究中,所有的MRSA分离株也被发现对替考拉宁敏感。与其他印度研究一样,对复方新诺明、红霉素、庆大霉素、其他青霉素和头孢菌素的耐药性似乎是本研究中MRSA分离株的一个共同特征。

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