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腹腔镜结肠癌切除术:一种肿瘤学上可行的选择。

Laparoscopic colectomy for cancer: an oncologic feasible option.

作者信息

Lin K M, Ota D M

机构信息

Division of Surgical Oncology, Ellis Fischel Cancer Center, University of Missouri School of Medicine, 115 Business Loop 70 West, 65203, Columbia, MO, USA.

出版信息

Surg Oncol. 2000 Nov;9(3):127-34. doi: 10.1016/s0960-7404(01)00002-0.

Abstract

The conventional and accepted treatment for curative resection of colon cancer is laparotomy with hemicolectomy for right or left sided lesions. The technique of colon resection through an open laparotomy incision is well known. Over the past several years, laparoscopically assisted colectomy has been developed and studied, following the explosion of laparoscopic technology from the cholecystectomy experience and with acquisition of advanced general laparoscopic techniques. The right, left or sigmoid colon can be mobilized and regional lymphadenectomy performed using laparoscopic instruments and video-imaging equipment. The advantage of laparoscopic colectomy is the use of small abdominal port site and wound incisions which translate to reduced postoperative pain and analgesic requirement, earlier return of bowel function and normal physical activities, and shorter hospital stay without increasing health care costs. Laparoscopic colectomy compares favorably with open colectomy in terms of surgical morbidity and mortality. The laparoscopic approach has been shown to be technically and oncologically feasible with equivalent lymph node harvest from mesenteric lymphadenectomy and achieves adequate proximal and distal margins of colonic resection. Despite initial early anecdotal reports of port site cancer recurrence in laparoscopically assisted colectomy, port site recurrence is rare and its incidence is similar to incisional recurrences in conventional open colectomy. Recent prospective comparative studies have demonstrated equivalent patient survival and equivalent local or distant colon cancer recurrences for open versus laparoscopic curative resection of colon cancer.

摘要

结肠癌根治性切除的传统且被认可的治疗方法是,针对右侧或左侧病变行剖腹半结肠切除术。通过剖腹手术切口进行结肠切除的技术广为人知。在过去几年中,随着腹腔镜技术从胆囊切除术经验中蓬勃发展并获得先进的普通腹腔镜技术,腹腔镜辅助结肠切除术得以发展并得到研究。使用腹腔镜器械和视频成像设备,可以游离右半结肠、左半结肠或乙状结肠并进行区域淋巴结清扫。腹腔镜结肠切除术的优点是腹部切口小,这意味着术后疼痛减轻、镇痛需求减少、肠功能和正常身体活动恢复更早、住院时间更短,且不会增加医疗费用。在手术并发症发生率和死亡率方面,腹腔镜结肠切除术与开放性结肠切除术相比具有优势。腹腔镜手术已被证明在技术上和肿瘤学上是可行的,肠系膜淋巴结清扫获取的淋巴结数量相当,并且能实现足够的结肠切除近端和远端切缘。尽管最初有早期传闻称腹腔镜辅助结肠切除术中存在切口部位癌症复发,但切口部位复发很少见,其发生率与传统开放性结肠切除术中的切口复发相似。最近的前瞻性比较研究表明,结肠癌开放性与腹腔镜根治性切除的患者生存率相当,局部或远处结肠癌复发情况也相当。

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