Department of Health Sciences, Division of Surgery, Veneziale Hospital, Molise University, Isernia, Italy.
Am J Surg. 2012 Jul;204(1):115-20. doi: 10.1016/j.amjsurg.2011.09.005. Epub 2011 Dec 16.
Standard laparoscopic colectomy (SLC) for cancer is a safe, feasible, and oncologically effective procedure with better short-term and similar long-term results of open colectomy. Conversely, owing to technical difficulties in colonic resection and full mesenteric dissection, single-incision laparoscopic colectomy (SILC) has been considered unsuitable for oncologic purposes. We compared the technical feasibility and early clinical outcomes of SLC and SILC for cancer.
In this prospective randomized clinical trial, 16 (50%) patients underwent SLC (10 left and 6 right) and 16 (50%) patients underwent SILC (8 left and 8 right).
Demographics, preoperative data, and characteristics of the tumor were similar. The mean number of resected lymph nodes was 16 ± 5 in the SLC and 18 ± 6 in the SILC group (P = NS). Surgical time was 124 ± 8 minutes and 147 ± 5 minutes, respectively (P = NS). Surgical mortality was nil and the major morbidity rate was 6.3% in both groups.
SILC for cancer is a technically feasible and safe oncologic procedure with short-term results similar to those obtained with a traditional laparoscopic approach.
标准腹腔镜结直肠切除术（SLC）治疗癌症是一种安全、可行且具有肿瘤学疗效的方法，其短期结果优于开腹结直肠切除术，而长期结果与之相似。然而，由于结肠切除和全肠系膜解剖的技术困难，单切口腹腔镜结直肠切除术（SILC）被认为不适合肿瘤学目的。我们比较了 SILC 和 SLC 治疗癌症的技术可行性和早期临床结果。
在这项前瞻性随机临床试验中，16 例（50%）患者接受了 SLC（10 例左半结肠切除术和 6 例右半结肠切除术），16 例（50%）患者接受了 SILC（8 例左半结肠切除术和 8 例右半结肠切除术）。
两组患者的人口统计学、术前数据和肿瘤特征相似。SLC 组和 SILC 组平均切除的淋巴结数分别为 16 ± 5 个和 18 ± 6 个（P = NS）。手术时间分别为 124 ± 8 分钟和 147 ± 5 分钟（P = NS）。两组均无手术死亡，主要并发症发生率为 6.3%。
SILC 治疗癌症是一种技术可行且安全的肿瘤学方法，其短期结果与传统腹腔镜方法相似。
