Araghizadeh F Y, Timmcke A E, Opelka F G, Hicks T C, Beck D E
Department of Colon and Rectal Surgery, Ochsner Clinic, New Orleans, Louisiana, USA.
Dis Colon Rectum. 2001 May;44(5):713-6. doi: 10.1007/BF02234572.
This study was designed to assess the medical and surgical treatment of colonoscopic perforations.
A retrospective review of colonoscopic perforations from 1970 to 1999 was performed.
In 30 years, 34,620 colonoscopies resulted in 31 (0.09 percent) perforations. Eighteen (58 percent) resulted from therapeutic colonoscopies, whereas 13 (42 percent) occurred after diagnostic colonoscopies. Sixteen perforations (52 percent) were identified during the procedure, 13 (42 percent) within 24 hours, and two (6 percent) within 48 hours. Twenty patients (65 percent) underwent surgical therapy, and 11 (35 percent) were treated medically with intestinal rest and intravenous antibiotics. In the medically treated group, one patient required rehospitalization for percutaneous drainage of an intra-abdominal abscess, and one patient died after requesting no further treatment because of an underlying terminal medical condition. Three patients failed medical treatment and required surgical intervention. One underwent repair with proximal diversion, whereas the remaining two received a colorrhaphy without resection or diversion. In the surgical treatment group, nine patients received colorrhaphy without diversion, seven underwent resection with primary anastomosis, and four had resection with diversion.
Selected patients with colonoscopic perforation may be safely treated nonoperatively. Surgical treatment is reserved for patients with a large perforation or diffuse peritonitis.
本研究旨在评估结肠镜检查穿孔的内科及外科治疗方法。
对1970年至1999年间的结肠镜检查穿孔病例进行回顾性分析。
30年间,34620例结肠镜检查中有31例(0.09%)发生穿孔。18例(58%)穿孔发生于治疗性结肠镜检查,13例(42%)发生于诊断性结肠镜检查后。16例(52%)穿孔在操作过程中被发现,13例(42%)在24小时内被发现,2例(6%)在48小时内被发现。20例患者(65%)接受了手术治疗,11例(35%)接受了内科治疗,包括肠道休息及静脉使用抗生素。在内科治疗组中,1例患者因腹腔内脓肿经皮引流而再次住院,1例患者因基础终末期疾病拒绝进一步治疗后死亡。3例患者内科治疗失败,需接受手术干预。1例接受近端转流修补术,其余2例接受无切除或转流的结肠缝合术。在手术治疗组中,9例患者接受无转流的结肠缝合术,7例接受切除并一期吻合术,4例接受切除并转流术。
部分结肠镜检查穿孔患者可安全地接受非手术治疗。手术治疗适用于穿孔较大或有弥漫性腹膜炎的患者。