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韩国结肠镜检查穿孔的发生率及处理

Incidence and management of colonoscopic perforations in Korea.

作者信息

Kang Hae Yeon, Kang Hyoun Woo, Kim Sang Gyun, Kim Joo Sung, Park Kyu-Joo, Jung Hyun Chae, Song In Sung

机构信息

Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.

出版信息

Digestion. 2008;78(4):218-23. doi: 10.1159/000190811. Epub 2009 Jan 13.

Abstract

BACKGROUND AND AIM

Despite the low incidence of perforation after endoscopic procedures in the colon, the increasing use of these procedures is likely to cause a commensurate increase in such problems. This study was undertaken to determine the incidence of iatrogenic perforation of the colon, to define clinical characteristics, and to assess the management of these complications.

METHODS

A retrospective review of the medical records was performed for all patients with iatrogenic colon perforations after endoscopy between January 2000 and June 2007.

RESULTS

Over this 7-year study period, a total of 20,660 sigmoidoscopies, 17,102 colonoscopies, and 6,772 therapeutic procedures were performed, and 53 (0.12%) perforations were determined to be related to endoscopy. A diagnostic procedure was undertaken in 26 of these 53 perforation cases (perforation rate, 0.07%; 1 per 1,452 procedures), and a therapeutic procedure in the remaining 27 (perforation rate, 0.40%; 1 per 251 procedures). Nineteen patients (36%) were treated conservatively, and the remaining 34 (64%) required surgical management. Endoscopic clipping was performed in 9 patients, and conservative treatment was possible in 7 patients with successful closure. No procedure-related mortality occurred.

CONCLUSIONS

Endoscopic repair of iatrogenic colon perforations with clips could reduce immediate operative intervention rates.

摘要

背景与目的

尽管结肠内镜手术后穿孔的发生率较低,但这些手术使用的增加可能会导致此类问题相应增加。本研究旨在确定结肠医源性穿孔的发生率,明确临床特征,并评估这些并发症的处理方法。

方法

对2000年1月至2007年6月期间所有内镜检查后发生医源性结肠穿孔的患者病历进行回顾性分析。

结果

在这7年的研究期间,共进行了20660例乙状结肠镜检查、17102例结肠镜检查和6772例治疗性手术,确定53例(0.12%)穿孔与内镜检查有关。在这53例穿孔病例中,26例进行了诊断性手术(穿孔率为0.07%,每1452例手术中有1例),其余27例进行了治疗性手术(穿孔率为0.40%,每251例手术中有1例)。19例患者(36%)接受了保守治疗,其余34例(64%)需要手术治疗。9例患者进行了内镜夹闭,7例患者成功闭合,可行保守治疗。未发生与手术相关的死亡。

结论

使用夹子对医源性结肠穿孔进行内镜修复可降低立即手术干预率。

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