Usman A, Kimyai-Asadi A, Stiller M J, Alam M
Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Pediatr Dermatol. 2001 Mar-Apr;18(2):123-6. doi: 10.1046/j.1525-1470.2001.018002123.x.
Lichen planus is often found in association with a variety of underlying conditions. In particular, liver diseases such as primary biliary cirrhosis, primary sclerosing cholangitis, hepatitis C, and hepatitis B have been implicated in cutaneous lichen planus. Of interest, there is mounting evidence that lichen planus-like eruptions can occur following administration of the hepatitis B vaccine, which has recently become a routine immunization in many parts of the world. We present what we believe to be the first North American case of lichenoid drug eruption associated with the hepatitis B vaccine and provide a brief review of other reported cases of lichenoid eruption seen following hepatitis B vaccination.
扁平苔藓常与多种潜在疾病相关。特别是，原发性胆汁性肝硬化、原发性硬化性胆管炎、丙型肝炎和乙型肝炎等肝脏疾病已被认为与皮肤扁平苔藓有关。有趣的是，越来越多的证据表明，接种乙型肝炎疫苗后可能会出现扁平苔藓样皮疹，而乙型肝炎疫苗最近已在世界许多地区成为常规免疫接种。我们报告了我们认为是北美首例与乙型肝炎疫苗相关的苔藓样药疹病例，并简要回顾了其他报道的接种乙型肝炎疫苗后出现苔藓样皮疹的病例。
