Goldberg D J, Silapunt S
Skin Laser and Surgery Specialists of New York and New Jersey, Mount Sinai School of Medicine, New York, New York, USA.
Dermatol Surg. 2001 May;27(5):434-6. doi: 10.1046/j.1524-4725.2001.00329.x.
Unwanted hair is a widespread cosmetic problem. Many temporary methods of hair removal have proved unsatisfactory. A variety of laser systems with varying wavelengths, pulse durations, and energy fluences are currently utilized for hair removal. Optimal laser parameters continue to require further investigation.
To evaluate the efficacy and safety of a long-pulse millisecond Nd:YAG hair removal laser utilizing fluences of either 50, 80, or 100 J/cm2.
Fifteen subjects were treated with a contact cooled 50 msec Nd:YAG laser at fluences 30, 50, or 100 J/cm2. Reduction in hair regrowth was measured at 3 months after treatment by comparing the terminal hair count to the baseline values. Potential complications were also evaluated.
Average hair reduction at 3 months after treatment was 29%, 29%, and 27% in areas treated with a 50-msec Nd:YAG laser at fluences of 50, 80, and 100 J/cm2, respectively. Although short-term blistering was noted in two subjects, no hyperpimentation, hypopigmentation, or scarring was observed at 3 months after treatment.
Long-pulse millisecond Nd:YAG laser hair removal with fluences of either 50, 80, or 100 J/cm2 leads to similar efficacy with no significant adverse effects.
多毛是一个普遍存在的美容问题。许多临时脱毛方法已被证明并不令人满意。目前，各种具有不同波长、脉冲持续时间和能量密度的激光系统被用于脱毛。最佳激光参数仍需进一步研究。
评估能量密度为50、80或100 J/cm²的长脉冲毫秒级Nd:YAG脱毛激光的疗效和安全性。
15名受试者接受了接触冷却的50毫秒Nd:YAG激光治疗，能量密度分别为30、50或100 J/cm²。在治疗后3个月，通过将终毛数量与基线值进行比较来测量毛发再生的减少情况。还评估了潜在的并发症。
在能量密度为50、80和100 J/cm²的50毫秒Nd:YAG激光治疗区域，治疗后3个月的平均毛发减少率分别为29%、29%和27%。虽然有两名受试者出现了短期水疱，但在治疗后3个月未观察到色素沉着、色素减退或瘢痕形成。
能量密度为50、80或100 J/cm²的长脉冲毫秒级Nd:YAG激光脱毛疗效相似，且无明显不良反应。
