用于脱毛的毫秒级钕钇铝石榴石激光的组织学评估。
Histologic evaluation of a millisecond Nd:YAG laser for hair removal.
作者信息
Goldberg D J, Silapunt S
机构信息
Skin Laser & Surgery Specialists of New York & New Jersey, NJ Medical School, Newark, New Jersey, USA.
出版信息
Lasers Surg Med. 2001;28(2):159-61. doi: 10.1002/lsm.1033.
BACKGROUND
Hirsutism and hypertrichosis are common problems. Laser-assisted hair removal has recently become a popular method to remove unwanted hair. However, histologic changes of the hair follicle after exposure to laser continue to require further investigation.
OBJECTIVE
To determine the thermal effect of a millisecond Nd:YAG hair removal laser.
METHODS
Six patients with black hair were treated with 50 msec pulsed Nd:YAG laser at fluences 30, 50 or 100 J/cm(2). Histologic examinations were performed on each laser-treated site at 24-72 hours after laser exposure.
RESULTS
Fluence-dependent selective thermal injury to follicles was seen. The average depth of acute laser injury at fluences 30, 50 and 100 J/cm(2) were 1.06, 0.85 and 1.11 millimeters, respectively.
CONCLUSIONS
Long-pulsed millisecond Nd:YAG lasers produce selective thermal damage of hair follicles. Varied laser fluences used in this study did not statistically alter the degree of thermal injury.
背景
多毛症和毛发过多是常见问题。激光辅助脱毛近来已成为去除多余毛发的常用方法。然而，毛囊在激光照射后的组织学变化仍需进一步研究。
目的
确定毫秒级掺钕钇铝石榴石脱毛激光的热效应。
方法
对6名黑发患者使用脉冲宽度为50毫秒的掺钕钇铝石榴石激光，能量密度分别为30、50或100 J/cm²进行治疗。在激光照射后24至72小时对每个激光治疗部位进行组织学检查。
结果
观察到能量密度依赖性的毛囊选择性热损伤。能量密度为30、50和100 J/cm²时，急性激光损伤的平均深度分别为1.06、0.85和1.11毫米。
结论
长脉冲毫秒级掺钕钇铝石榴石激光会对毛囊产生选择性热损伤。本研究中使用的不同激光能量密度在统计学上并未改变热损伤程度。
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