Leichnetz G R
Department of Anatomy, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia 23298-0709, USA.
Anat Rec. 2001 Jun 1;263(2):215-36. doi: 10.1002/ar.1082.
The afferent and efferent cortical and subcortical connections of the medial posterior parietal cortex (area 7m) were studied in cebus (Cebus apella) and macaque (Macaca fascicularis) monkeys using the retrograde and anterograde capabilities of the horseradish peroxidase (HRP) technique. The principal intraparietal corticocortical connections of area 7m in both cebus and macaque cases were with the ipsilateral medial bank of the intraparietal sulcus (MIP) and adjacent superior parietal lobule (area 5), inferior parietal lobule (area 7a), lateral bank of the IPS (area 7ip), caudal parietal operculum (PGop), dorsal bank of the caudal superior temporal sulcus (visual area MST), and medial prestriate cortex (including visual area PO and caudal medial lobule). Its principal frontal corticocortical connections were with the prefrontal cortex in the shoulder above the principal sulcus and the cortex in the shoulder above the superior ramus of the arcuate sulcus (SAS), the area purported to contain the smooth eye movement-related frontal eye field (FEFsem) in the cebus monkey by other investigators. There were moderate connections with the cortex in the rostral bank of the arcuate sulcus (purported to contain the saccade-related frontal eye field; FEFsac), supplementary eye field (SEF), and rostral dorsal premotor area (PMDr). Area 7m also had major connections with the cingulate cortex (area 23), particularly the ventral bank of the cingulate sulcus. The principal subcortical connections of area 7m were with the dorsal portion of the ventrolateral thalamic (VLc) nucleus, lateral posterior thalamic nucleus, lateral pulvinar, caudal mediodorsal thalamic nucleus and medial pulvinar, central lateral, central superior lateral, and central inferior intralaminar thalamic nuclei, dorsolateral caudate nucleus and putamen, middle region of the claustrum, nucleus of the diagonal band, zona incerta, pregeniculate nucleus, anterior and posterior pretectal nuclei, intermediate layer of the superior colliculus, nucleus of Darkschewitsch and dorsomedial parvicellular red nucleus (macaque cases only), dorsal, dorsolateral and lateral basilar pontine nuclei, nucleus reticularis tegmenti pontis, locus ceruleus, and superior central nucleus. The findings are discussed in terms of the possibility that area 7m contains a "medial parietal eye field" and belongs to a neural network of oculomotor-related structures that plays a role in the control of eye movement.
利用辣根过氧化物酶（HRP）技术的逆行和顺行能力，在卷尾猴（僧帽猴属）和猕猴（猕猴属）中研究了内侧后顶叶皮质（7m区）的传入和传出皮质及皮质下连接。在卷尾猴和猕猴中，7m区主要的顶叶皮质间连接均与顶内沟（MIP）的同侧内侧壁、相邻的顶上小叶（5区）、顶下小叶（7a区）、顶内沟外侧壁（7ip区）、顶叶尾侧盖（PGop）、颞上沟尾侧背壁（视觉区MST）以及内侧纹前皮质（包括视觉区PO和尾侧内侧小叶）有关。其主要的额叶皮质间连接与中央沟上方肩部的前额叶皮质以及弓形沟上支上方肩部的皮质有关，其他研究者认为卷尾猴的该区域包含与平稳眼动相关的额叶眼区（FEFsem）。与弓形沟吻侧壁的皮质（据称包含与扫视相关的额叶眼区；FEFsac）、辅助眼区（SEF）以及吻侧背侧运动前区（PMDr）有适度连接。7m区还与扣带回皮质（23区）有主要连接，特别是扣带沟的腹侧壁。7m区主要的皮质下连接与腹外侧丘脑（VLc）核的背侧部分、丘脑外侧后核、外侧枕核、丘脑尾侧背内侧核和内侧枕核、中央外侧核、中央上外侧核和中央下板内核、背外侧尾状核和壳核、屏状核中部、斜角带核、未定带、外侧膝状体前核、前顶盖前核和后顶盖前核、上丘中间层、达克谢维奇核和背内侧小细胞红核（仅猕猴）、背侧、背外侧和外侧脑桥基底核、脑桥被盖网状核、蓝斑核和中央上核有关。根据7m区可能包含“内侧顶叶眼区”且属于在眼动控制中起作用的动眼相关结构神经网络这一可能性对研究结果进行了讨论。
