Suppr超能文献

使用阿托斯钕钇铝石榴石3.5毫秒脉冲激光脱毛:一项为期3个月的临床研究。

Hair removal with an Athos Nd:YAG 3.5 ms pulse laser: a 3-month clinical study.

作者信息

Fournier N, Aghajan-Nouri N, Barneon G, Mordon S

机构信息

Centre Commercial La Croisée, Clapiers, France.

出版信息

J Cutan Laser Ther. 2000 Sep;2(3):125-30. doi: 10.1080/14628830050516362.

Abstract

INTRODUCTION/OBJECTIVE: This study aimed to evaluate the safety and efficacy of a 3.5 ms Nd:YAG laser for the removal of hair in subjects with Fitzpatrick skin types I-IV. Thanks to a pulse shorter than the hair Thermal Relaxation time (TRT), photothermolysis was thus achieved.

METHODS

This study assessed the percentage of hair reduction at 1 month and at 3 months after a single Nd:YAG laser treatment (Athos; Quantel Médical, France); 3.5 ms pulse, single shot to 3 Hz, a maximum fluence of 80 J/cm2, 4 mm spot, no cooling system, no anaesthesia. The treatment sites consisted of three adjacent squares (optimum fluence, no treatment, -20% optimum fluence). Computerized hair counting was realized on digital pictures. The phototype, pain, side effects and patient's satisfaction were noted. Biopsies were performed 15 min after treatment. The enrolment consisted of 17 women, 22-60 years old, phototypes I-IV, with a follow-up at 1 month and 3 months of 25 sites.

RESULTS

Counting at 1 month and at 3 months revealed a significant hair reduction compared with the control sites: 60% at 1 month (P < 0.001) and 24% at 3 months (P < 0.05) for optimal fluence (25-80 J/cm2), compared with 31% and 0% on the control sites; values similar to those published for Nd:YAG or diode lasers. There were no adverse effects at all. Biopsies showed lesions from necrosis coagulation of the root sheaths and hair disruption to isolated apoptotic cells in the outer root sheath, depending on the fluence applied.

CONCLUSION

Results from this study show that the Athos Nd:YAG is efficient and safe for removing pigmented hair in phototypes I-IV.

摘要

引言/目的:本研究旨在评估3.5毫秒掺钕钇铝石榴石(Nd:YAG)激光用于去除Fitzpatrick皮肤分型为I - IV型受试者毛发的安全性和有效性。由于脉冲短于毛发热弛豫时间(TRT),从而实现了光热解。

方法

本研究评估单次Nd:YAG激光治疗(Athos;法国Quantel Médical公司)后1个月和3个月时的毛发减少百分比;3.5毫秒脉冲,单次发射至3赫兹,最大能量密度80 J/cm²,光斑4毫米,无冷却系统,无麻醉。治疗部位由三个相邻方块组成(最佳能量密度、未治疗、比最佳能量密度低20%)。通过数码照片进行计算机化毛发计数。记录皮肤分型、疼痛、副作用及患者满意度。治疗后15分钟进行活检。入组者为17名年龄在22至60岁、皮肤分型为I - IV型的女性,对25个部位进行1个月和3个月的随访。

结果

1个月和3个月时的计数显示,与对照部位相比毛发显著减少:最佳能量密度(25 - 80 J/cm²)下,1个月时减少60%(P < 0.001),3个月时减少24%(P < 0.05),而对照部位分别为31%和0%;这些数值与已发表的Nd:YAG或二极管激光的数值相似。完全没有不良反应。活检显示,根据所施加的能量密度不同,从毛根鞘的坏死凝固和毛发破坏到外根鞘中孤立的凋亡细胞均有病变。

结论

本研究结果表明,Athos Nd:YAG激光在去除I - IV型皮肤色素性毛发方面有效且安全。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验