Schiemann U, Steins M, Knospe V, Riedasch M, Domschke W, Stoll R
Department of Medicine, University of Muenster, Germany.
AIDS Patient Care STDS. 1999 Jan;13(1):7-9. doi: 10.1089/apc.1999.13.7.
A 37-year-old man with hemophilia B, acquired immunodeficiency syndrome, and a unilateral cytomegalovirus retinitis developed a central retinal vein occlusion. This vascular complication occurred despite effective antiviral drug treatment with improvement of the fundus and despite decreased blood coagulability due to hemophilia B. Additional analyses of thrombophilic parameters did not reveal hints of systemic thrombophilia, suggesting that toxic and inflammatory effects of cytomegalovirus itself were responsible for the ophthalmologic aggravation.
一名患有乙型血友病、获得性免疫缺陷综合征且单侧患有巨细胞病毒性视网膜炎的37岁男性发生了视网膜中央静脉阻塞。尽管进行了有效的抗病毒药物治疗且眼底情况有所改善,尽管乙型血友病导致血液凝固性降低,但这种血管并发症仍发生了。对血栓形成倾向参数的进一步分析未发现系统性血栓形成倾向的迹象,这表明巨细胞病毒本身的毒性和炎症作用是导致眼科病情加重的原因。