Liu J, Li X, Hu X
Suzhou Maternity and Infant Health Institute, Jiangsu(215004).
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1998 Mar;18(3):145-7.
To explore the mechanism of treating endometriosis by tonifying Kidney and removing blood stasis with Neiyixiao Recipe (NYXR).
One hundred and three patients of endometriosis were divided randomly into the NYXR group (58 cases, treated with NYXR) and the control group (45 cases, treated with danazol) and were reviewed for the improvement of clinical symptoms, serum level of FSH, LH, PRL, E2, P and T, humoral and cellular immunity (C3, C4, CD3, CD4, CD8), and plasma prostaglandin after treatment.
There was no significant difference in effect between the NYXR group and the control group in relief of dysmenorrhea and degradation of elevated plasma prostaglandin (chi 2 = 0.71, P > 0.05). But there was significant difference between the two groups in curing infertility (chi 2 = 14.77, P < 0.01), and the effect of NYXR in regulating endocrine and immunity was significantly better than that of danazol.
By tonifying Kidney and removing blood stasis, NYXR is multi-effective and being one of effective methods in clinical practice for treatment of endometriosis.
探讨内异消方补肾化瘀治疗子宫内膜异位症的作用机制。
将103例子宫内膜异位症患者随机分为内异消方组（58例，采用内异消方治疗）和对照组（45例，采用达那唑治疗），观察治疗后临床症状改善情况、血清卵泡刺激素（FSH）、黄体生成素（LH）、催乳素（PRL）、雌二醇（E2）、孕酮（P）及睾酮（T）水平、体液免疫及细胞免疫指标（C3、C4、CD3、CD4、CD8）和血浆前列腺素变化。
内异消方组与对照组在缓解痛经及降低血浆前列腺素升高方面疗效无显著差异（χ2 = 0.71，P > 0.05）。但两组在治疗不孕方面有显著差异（χ2 = 14.77，P < 0.01），且内异消方在调节内分泌及免疫方面的效果明显优于达那唑。
内异消方补肾化瘀，疗效多样且是临床治疗子宫内膜异位症的有效方法之一。
