Behera D, Chakrabarti T, Khanduja K L
Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh-160 012, India.
Indian J Chest Dis Allied Sci. 2001 Jan-Mar;43(1):27-31.
The effect of indoor air pollution due to domestic cooking with biomass fuel and liquefied petroleum gas (LPG) on the course of bronchial asthma was examined in one hundred non-smoking female asthmatics. The parameters for evaluation were symptoms, emergency visits, and drug requirements. The patients also measured peak expiratory flow rate (PEFR) at home five times daily over a period of one week and the levels of carboxyhaemoglobin (COHb) were estimated randomly during clinic visits. The COHb levels (%) were 4.1 +/- 0.9 and 3.5 +/- 0.6 in the two groups with 22-30% of the subjects reporting increased symptoms during cooking. The number of emergency admissions and the daily requirement of steroids were comparable in both the groups. The PEFR values were lower than the predicted values in both the groups at all times. Further, the readings after exposure to cooking fuels were lower than those before cooking in both the groups (p < 0.01) and these values were similar to those observed during early morning records at 6 AM, which were the lowest. It was concluded that exposure to biomass fuel and LPG affect pulmonary function (PEFR) in asthmatics and both types of fuels affect the airway function and symptoms of bronchial asthma in a similar manner.
在100名不吸烟的女性哮喘患者中，研究了使用生物质燃料和液化石油气（LPG）进行家庭烹饪所导致的室内空气污染对支气管哮喘病程的影响。评估参数包括症状、急诊就诊次数和药物需求。患者还在一周的时间里每天在家中测量5次呼气峰值流速（PEFR），并在门诊就诊时随机估算碳氧血红蛋白（COHb）水平。两组患者的COHb水平（%）分别为4.1±0.9和3.5±0.6，22 - 30%的受试者报告在烹饪期间症状加重。两组的急诊入院次数和类固醇的每日需求量相当。两组在所有时间点的PEFR值均低于预测值。此外，两组在接触烹饪燃料后的读数均低于烹饪前（p < 0.01），且这些值与凌晨6点的清晨记录值相似，而清晨记录值是最低的。得出的结论是，接触生物质燃料和LPG会影响哮喘患者的肺功能（PEFR），且两种燃料对支气管哮喘的气道功能和症状的影响方式相似。
