de Pierro A R, Beleza Yamagishi M E
State University of Campinas, Department of Applied Mathematics, SP, Brazil.
IEEE Trans Med Imaging. 2001 Apr;20(4):280-8. doi: 10.1109/42.921477.
The maximum-likelihood (ML) approach in emission tomography provides images with superior noise characteristics compared to conventional filtered backprojection (FBP) algorithms. The expectation-maximization (EM) algorithm is an iterative algorithm for maximizing the Poisson likelihood in emission computed tomography that became very popular for solving the ML problem because of its attractive theoretical and practical properties. Recently, (Browne and DePierro, 1996 and Hudson and Larkin, 1994) block sequential versions of the EM algorithm that take advantage of the scanner's geometry have been proposed in order to accelerate its convergence. In Hudson and Larkin, 1994, the ordered subsets EM (OS-EM) method was applied to the ML problem and a modification (OS-GP) to the maximum a posteriori (MAP) regularized approach without showing convergence. In Browne and DePierro, 1996, we presented a relaxed version of OS-EM (RAMLA) that converges to an ML solution. In this paper, we present an extension of RAMLA for MAP reconstruction. We show that, if the sequence generated by this method converges, then it must converge to the true MAP solution. Experimental evidence of this convergence is also shown. To illustrate this behavior we apply the algorithm to positron emission tomography simulated data comparing its performance to OS-GP.
与传统的滤波反投影(FBP)算法相比,发射断层扫描中的最大似然(ML)方法能够提供具有更优噪声特性的图像。期望最大化(EM)算法是一种用于在发射计算机断层扫描中最大化泊松似然的迭代算法,因其具有吸引人的理论和实际特性,在解决ML问题时变得非常流行。最近,(Browne和DePierro,1996年;Hudson和Larkin,1994年)为了加速收敛,提出了利用扫描仪几何结构的EM算法的块序贯版本。在Hudson和Larkin,1994年,有序子集EM(OS-EM)方法被应用于ML问题,并对最大后验(MAP)正则化方法进行了一种修改(OS-GP),但未展示收敛情况。在Browne和DePierro,1996年,我们提出了一种收敛到ML解的OS-EM松弛版本(RAMLA)。在本文中,我们提出了用于MAP重建的RAMLA扩展。我们表明,如果该方法生成的序列收敛,那么它必定收敛到真实的MAP解。还展示了这种收敛的实验证据。为了说明这种行为,我们将该算法应用于正电子发射断层扫描模拟数据,并将其性能与OS-GP进行比较。