Surer I, Baker L A, Jeffs R D, Gearhart J P
Division of Pediatric Urology, Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
J Urol. 2001 Jun;165(6 Pt 2):2438-40. doi: 10.1016/S0022-5347(05)66224-6.
Achievement of urinary continence in patients with the exstrophy-epispadias complex remains a challenge. We reviewed our experience with the modified Young-Dees-Leadbetter bladder neck repair in patients with bladder exstrophy who underwent primary bladder closure elsewhere.
We retrospectively reviewed exstrophy charts and database of 57 male and 11 female with classic bladder exstrophy who underwent bladder neck repair at our institute and successful primary bladder closure elsewhere during the last 2 decades. Osteotomy was performed at primary closure in 14 (20%) cases and 9 (13%) patients at bladder neck repair in 9 (13%) to aid in stabilizing the urethra and pelvic ring, and to help reapproximate the pelvic floor musculature facilitating urinary continence.
Primary closure was done within 72 hours of life elsewhere in 41 (60%) patients, and between ages 72 hours and 5 years (most during the first month of life) in 27. Paraexstrophy skin flaps were used in 33 (48%) cases, and the most common complication was bladder outlet obstruction of the posterior urethra secondary to the skin flaps. Of the 68 patients 57 (83%) are continent and voiding per urethra without need for augmentation or clean intermittent catheterization, 9 (13%) required clean intermittent catheterization including 7 who underwent continent urinary diversion after failed bladder neck repair, and 2 are still incontinent due to a severe posterior urethral stricture. Urinary retention was the most common symptom after bladder neck repair which resolved following catheter dilation or prolonged suprapubic catheter drainage.
Successful early primary closure of a good bladder template is the most important determinant of eventual bladder capacity and compliance.
实现膀胱外翻-尿道上裂综合征患者的尿失禁控制仍然是一项挑战。我们回顾了在其他地方接受初次膀胱闭合术的膀胱外翻患者中进行改良Young-Dees-Leadbetter膀胱颈修复术的经验。
我们回顾性分析了过去20年内在我院接受膀胱颈修复术且在其他地方成功进行初次膀胱闭合术的57例男性和11例女性经典膀胱外翻患者的病历和数据库。14例(20%)患者在初次闭合时进行了截骨术,9例(13%)患者在膀胱颈修复时进行了截骨术,以帮助稳定尿道和骨盆环,并有助于重新对合盆底肌肉组织以促进尿失禁控制。
41例(60%)患者在出生后72小时内在其他地方完成了初次闭合,27例在出生后72小时至5岁之间(大多数在出生后的第一个月内)完成。33例(48%)患者使用了膀胱旁皮肤瓣,最常见的并发症是继发于皮肤瓣的后尿道膀胱出口梗阻。68例患者中,57例(83%)实现了控尿且经尿道排尿,无需膀胱扩大术或清洁间歇性导尿,9例(13%)需要清洁间歇性导尿,其中7例在膀胱颈修复失败后接受了可控性尿流改道,2例因严重的后尿道狭窄仍存在尿失禁。膀胱颈修复术后最常见的症状是尿潴留,经导管扩张或长期耻骨上导管引流后症状缓解。
成功早期对良好的膀胱模板进行初次闭合是最终膀胱容量和顺应性的最重要决定因素。