Munir A, Hussain S A, Sondhi D, Ameh J, Rosner F
Department of Medicine, Mount Sinai Services at Queens Hospital Center, Jamaica, NY 11432, USA.
Mt Sinai J Med. 2001 May;68(3):216-8.
Wernicke's encephalopathy, a serious neurological disorder caused by thiamine deficiency, is most commonly found in chronic alcoholics. We present a typical case of Wernicke's encephalopathy in a non-alcoholic man. Our patient presented with altered mental status, slurred speech, fever, vomiting and headache of one-week duration. An infectious etiology of the symptoms was ruled out by spinal fluid cultures. The patient improved dramatically within 24 hours of administration of thiamine.
韦尼克脑病是一种由硫胺素缺乏引起的严重神经系统疾病,最常见于慢性酗酒者。我们报告一例非酗酒男性的典型韦尼克脑病病例。我们的患者出现精神状态改变、言语不清、发热、呕吐及持续一周的头痛。脑脊液培养排除了症状的感染性病因。患者在给予硫胺素后24小时内病情显著改善。