Harris M I
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 6707 Democracy Blvd., Bethesda, MD 20892-5460, USA.
Diabetes Care. 2001 Jun;24(6):979-82. doi: 10.2337/diacare.24.6.979.
The aim of the study was to investigate the relationship between blood glucose level, measured as HbA(1c), and frequency of self-monitoring in patients with type 2 diabetes. Daily self-monitoring is believed to be important for patients treated with insulin or oral agents to detect asymptomatic hypoglycemia and to guide patient and provider behavior toward reaching blood glucose goals.
A national sample of patients with type 2 diabetes was studied in the third National Health and Nutrition Examination Survey. Data on therapy for diabetes, frequency of self-monitoring of blood glucose, and HbA(1c) values were obtained by structured questionnaires and by clinical and laboratory assessments.
According to the data, 29% of patients treated with insulin, 65% treated with oral agents, and 80% treated with diet alone had never monitored their blood glucose or monitored it less than once per month. Self-monitoring at least once per day was practiced by 39% of those taking insulin and 5-6% of those treated with oral agents or diet alone. For all patients combined, the proportion of patients who tested their blood glucose increased with an increasing HbA(1c) value. However, when examined by diabetes therapy category, there was little relationship between HbA(1c) value and the proportion testing at least once per day or the proportion testing at least once per week.
In this cross-sectional study of patients with type 2 diabetes, the increase in frequency of self-monitoring of blood glucose with increasing HbA(1c) value was associated with the higher proportion of insulin-treated patients in higher HbA(1c) categories. Within diabetes therapy categories, the frequency of self-monitoring was not related to glycemic control, as measured by HbA(1c) level.
本研究旨在调查以糖化血红蛋白(HbA1c)衡量的血糖水平与2型糖尿病患者自我血糖监测频率之间的关系。对于接受胰岛素或口服药物治疗的患者而言,日常自我血糖监测被认为对于检测无症状性低血糖以及指导患者和医护人员朝着实现血糖目标的行为非常重要。
在第三次全国健康与营养检查调查中,对全国范围内的2型糖尿病患者样本进行了研究。通过结构化问卷以及临床和实验室评估获取了糖尿病治疗、自我血糖监测频率和HbA1c值的数据。
根据数据,29%接受胰岛素治疗的患者、65%接受口服药物治疗的患者以及80%仅接受饮食治疗的患者从未进行过血糖监测或每月监测次数少于一次。39%接受胰岛素治疗的患者以及5 - 6%接受口服药物或仅接受饮食治疗的患者每天至少进行一次自我血糖监测。对于所有患者而言,血糖检测患者的比例随着HbA1c值的升高而增加。然而,按糖尿病治疗类别进行检查时,HbA1c值与每天至少检测一次的比例或每周至少检测一次的比例之间几乎没有关系。
在这项针对2型糖尿病患者的横断面研究中,随着HbA1c值升高,自我血糖监测频率的增加与HbA1c类别较高的胰岛素治疗患者比例较高有关。在糖尿病治疗类别中,自我血糖监测频率与以HbA1c水平衡量的血糖控制无关。