Mamtora Sunil, Maghsoudlou Panayiotis, Hasan Hani, Zhang Wenrui, El-Ashry Mohamed
Department of Ophthalmology, Great Western Hospital, Swindon SN3 6BB, UK.
Department of Developmental Biology, University College London, London WC1E 6BT, UK.
Clin Ophthalmol. 2021 Jan 7;15:41-47. doi: 10.2147/OPTH.S287531. eCollection 2021.
BACKGROUND/AIMS: Effective management of diabetic retinopathy requires multidisciplinary input. We aimed to evaluate the impact of point of care (POC) HbA1c testing as a tool to identify patients most in need of specialist diabetologist input and assess the accuracy and determinants of patients' insight into their glycaemic and blood pressure control.
Forty-nine patients with diabetic retinopathy were recruited from the eye clinic at Great Western Hospital. Patients completed a questionnaire and POC HbA1c and blood pressure values were measured. Statistical analysis was completed with SPSS v23.
Mean age was 64.4 years, median interval since the last formal HbA1c reading was 10.2 months and the mean POC HbA1c was 64.1 mmol/mol. HbA1c significantly correlated with the degree of retinopathy. Of the patients, 81.6% had POC readings above the levels recommended by the National Institute for Health and Care Excellence, with only 16.3% having insight into this. Insight to HbA1c levels was predicted by age but not by duration of disease. Fourteen patients (33.3%) identified with high HbA1c readings were referred to secondary diabetic services and 88.8% of patients felt that the test was useful and likely to improve their diabetic control.
The majority of patients had poor insight into their diabetes control, with sub-optimal treatment and follow-up. Poor insight is high in younger patients, suggesting that POC HbA1c testing is particularly important in educating younger patients who may be Type 1 diabetics with more severe disease. POC HbA1c represents a cost-effective, reproducible and clinically significant tool for the management of diabetes in an outpatient ophthalmology setting, allowing the rapid recognition of high-risk patients and appropriate referral to secondary diabetic services.
背景/目的:糖尿病视网膜病变的有效管理需要多学科的参与。我们旨在评估即时检测(POC)糖化血红蛋白(HbA1c)作为一种工具的影响,以识别最需要糖尿病专科医生参与的患者,并评估患者对其血糖和血压控制的了解程度的准确性及决定因素。
从大西部医院眼科门诊招募了49例糖尿病视网膜病变患者。患者完成一份问卷,并测量即时检测的HbA1c和血压值。使用SPSS v23进行统计分析。
平均年龄为64.4岁,自上次正式HbA1c检测以来的中位间隔时间为10.2个月,即时检测的平均HbA1c为64.1 mmol/mol。HbA1c与视网膜病变程度显著相关。在患者中,81.6%的即时检测结果高于英国国家卫生与临床优化研究所推荐的水平,只有16.3%的患者了解这一点。对HbA1c水平的了解程度由年龄预测,而非疾病持续时间。14例(33.3%)HbA1c检测结果高的患者被转诊至二级糖尿病服务机构,88.8%的患者认为该检测有用且可能改善其糖尿病控制情况。
大多数患者对其糖尿病控制情况了解不足,治疗和随访不理想。年轻患者中了解不足的情况较多,这表明即时检测HbA1c在教育可能患有更严重疾病的1型糖尿病年轻患者方面尤为重要。即时检测HbA1c是门诊眼科环境中管理糖尿病的一种具有成本效益、可重复且具有临床意义的工具,可快速识别高危患者并适当转诊至二级糖尿病服务机构。