微生物基因组：应对多样性。

Microbial genomes: dealing with diversity.

作者信息

Boucher Y, Nesbø C L, Doolittle W F

机构信息

Canadian Institute for Advanced Research Program in Evolutionary Biology, Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia BSH 4H7, Canada.

出版信息

Curr Opin Microbiol. 2001 Jun;4(3):285-9. doi: 10.1016/s1369-5274(00)00204-6.

DOI:10.1016/s1369-5274(00)00204-6

PMID:11378480

Abstract

We have now complete genome sequences of several pairs of closely related prokaryotes (conspecific strains or congeneric species). Surprisingly, even strains of the same species can differ by as much as 20% in gene content. Conceptual and methodological approaches for dealing with such diversity are now being developed, and should transform microbial genomics.

摘要

我们现已获得几对亲缘关系密切的原核生物（同种菌株或同属物种）的完整基因组序列。令人惊讶的是，即使是同一物种的菌株，其基因含量也可能相差多达20%。目前正在开发处理这种多样性的概念和方法，这将改变微生物基因组学。