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三个非洲国家人工流产和自然流产的并发症:一项在世卫组织合作中心开展的基于医院的研究

Complications of induced abortion and miscarriage in three African countries: a hospital-based study among WHO collaborating centers.

作者信息

Goyaux N, Alihonou E, Diadhiou F, Leke R, Thonneau P F

机构信息

Human Fertility Research Group, Toulouse, France.

出版信息

Acta Obstet Gynecol Scand. 2001 Jun;80(6):568-73.

PMID:11380296
Abstract

OBJECTIVE

The aim of this study was to describe two of the outcomes of pregnancy, induced abortion and miscarriage, in three African countries. Major maternal risk factors were also evaluated.

METHODS

The study was prospective and based on the medical files of all 1,957 women admitted to participating health care structures.

RESULTS

Overall, 988 women were admitted for complications of miscarriage, and 969 for complications of induced abortion. Gestational age was lower in women with miscarriages (p<0.002). The level of use of contraceptive methods ((p<0.003) and educational level ((p<0.005) were lower in women who had had an induced abortion. In our study, 26 maternal deaths were recorded, 22 of which were associated with induced abortion. Infection was the most important risk factor for death (OR=4.8; 1.9-12.4).

CONCLUSION

Maternal deaths related to abortion complications often occurred shortly after hospital admission and with signs of sepsis. This demonstrates the importance of effective emergency services. Unfortunately, hospital-based studies alone cannot assess all maternal death risk factors, especially those for maternal death related to induced abortion complications. It is therefore important to determine what happened to the woman before hospital admission and during her stay in hospital. Combinations of qualitative and quantitative methods could be used to increase our understanding of this problem and to help us to solve it.

摘要

目的

本研究旨在描述三个非洲国家妊娠的两种结局,即人工流产和自然流产,并评估主要的孕产妇风险因素。

方法

该研究为前瞻性研究,基于所有1957名入住参与研究的医疗机构的女性的医疗档案。

结果

总体而言,988名女性因自然流产并发症入院,969名因人工流产并发症入院。自然流产女性的孕周较低(p<0.002)。人工流产女性的避孕方法使用率(p<0.003)和教育水平(p<0.005)较低。在我们的研究中,记录了26例孕产妇死亡,其中22例与人工流产有关。感染是最重要的死亡风险因素(比值比=4.8;1.9 - 12.4)。

结论

与流产并发症相关的孕产妇死亡通常在入院后不久发生,并伴有败血症迹象。这表明了有效的急诊服务的重要性。不幸的是,仅基于医院的研究无法评估所有孕产妇死亡风险因素,尤其是与人工流产并发症相关的孕产妇死亡风险因素。因此,确定女性在入院前和住院期间发生了什么很重要。可以使用定性和定量方法相结合的方式来增进我们对这个问题的理解并帮助我们解决它。

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