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硬化萎缩性苔藓累及手腕和左脚踝,临床症状类似扁平苔藓。

Lichen sclerosus et atrophicus affecting the wrists and left ankle and clinically simulating lichen planus.

作者信息

Corbalán-Vélez R, Pérez-Ferriols A

机构信息

Department of Dermatology, University Clinic Hospital Lozano Blesa, Zaragoza, Spain.

出版信息

Cutis. 2001 May;67(5):417-9.

Abstract

Lichen sclerosus et atrophicus (LSA) is a disease of unknown etiology, although hereditary, endocrine, and autoimmune factors are known to be involved. Although the anal and genital regions are predominantly affected, 2.5% of patients only present with extragenital lesions--particularly of the trunk, neck, and upper limbs. The wrists, palmoplantar regions, nipples, and face are less commonly involved. The possible relationship between LSA and both lichen planus and localized scleroderma (morphea) has not been clearly established, although in a number of cases, several of these conditions have been found simultaneously. We report the case of a 61-year-old woman with LSA lesions affecting only the wrists and left ankle. The unusual character of this presentation is pointed out, along with its clinical similarity to lichen planus.

摘要

硬化萎缩性苔藓(LSA)是一种病因不明的疾病,尽管已知其与遗传、内分泌和自身免疫因素有关。虽然肛门和生殖器区域是主要受累部位,但2.5%的患者仅表现为生殖器外病变——特别是躯干、颈部和上肢。手腕、掌跖部位、乳头和面部较少受累。LSA与扁平苔藓和局限性硬皮病(硬斑病)之间的可能关系尚未明确确立,尽管在一些病例中,已同时发现这几种情况。我们报告一例61岁女性,其LSA病变仅累及手腕和左脚踝。指出了这种表现的不寻常特征及其与扁平苔藓的临床相似性。

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