Lessani T, Gallego H, Lynch P J
University of California, Davis, USA.
Cutis. 1998 Feb;61(2):103-4.
Lichen planus and lichen sclerosus share several common features, including lymphocytic infiltration at the dermal-epidermal junction, clinical involvement of both skin and mucosa, erosive disease of mucosal surfaces, and the occasional occurrence of squamous cell carcinoma at the site of chronic, erosive mucosal lesions. In spite of these similarities, there are remarkably few reports of patients who concurrently have evidence of both diseases. We report a patient who had oral lesions of lichen planus and penile lesions of lichen sclerosus and we review possible mechanisms to explain this association.
扁平苔藓和硬化性苔藓有几个共同特征,包括真皮-表皮交界处的淋巴细胞浸润、皮肤和黏膜均受累、黏膜表面糜烂性病变以及慢性糜烂性黏膜病变部位偶尔发生鳞状细胞癌。尽管有这些相似之处,但同时患有这两种疾病证据的患者报告却非常少。我们报告了一例患有扁平苔藓口腔病变和硬化性苔藓阴茎病变的患者,并回顾了解释这种关联的可能机制。