Batra A S, Lewis A B
Division of Cardiology, Childrens Hospital Los Angeles and the University of Southern California Los Angeles, California 90027, USA.
Curr Opin Pediatr. 2001 Jun;13(3):234-9. doi: 10.1097/00008480-200106000-00004.
Myocarditis is defined as inflammation of the myocardium accompanied by myocellular necrosis. Acute myocarditis must be considered in patients who present with recent onset of cardiac failure or arrhythmia. Often there is a history of an antecedent flu-like illness. Fulminant myocarditis is a distinct entity characterized by sudden onset of severe congestive heart failure or cardiogenic shock, usually following a flu-like illness. Giant cell myocarditis is a rare, frequently fatal disorder of unknown origin characterized by presence of giant cell inflammatory infiltrate in the myocardium. In recent years we have made good progress in understanding the causes, pathogenesis, natural history, diagnosis, and treatment of myocarditis. However, our knowledge is still far from complete. New information that extends our understanding of myocarditis is being reported constantly. This review summarizes recent advances in myocarditis, with an emphasis on the literature during the last year.
心肌炎的定义为心肌炎症伴肌细胞坏死。对于近期出现心力衰竭或心律失常的患者，必须考虑急性心肌炎。通常有前驱流感样疾病史。暴发性心肌炎是一种独特的疾病，其特征为严重充血性心力衰竭或心源性休克突然发作，通常发生在流感样疾病之后。巨细胞心肌炎是一种罕见的、常致命的病因不明的疾病，其特征是心肌中存在巨细胞炎性浸润。近年来，我们在理解心肌炎的病因、发病机制、自然病程、诊断和治疗方面取得了良好进展。然而，我们的认识仍远未完善。不断有新信息报道，扩展了我们对心肌炎的认识。本综述总结了心肌炎的最新进展，重点关注去年的文献。
