Matsuura H
First Department of Internal Medicine, Hiroshima University Faculty of Medicine.
Nihon Rinsho. 2001 May;59(5):907-12.
It is well known that the pathogenesis of essential hypertension is multi-factorial, and that the environmental and genetic factors and their interaction play important roles on pathogenesis of hypertension. The environmental factors consist of natural environmental factors, such as weather, seasons, temperature, soil and water, and social environmental factors, such as human relationship, socioeconomic status, residence, education, stress and life-style. Life-style modification including salt restriction, body weight reduction, mineral supplementation, aerobic exercise, alcohol restriction, cessation of smoking and release from psychoemotional stress is the basic strategy for antihypertensive therapy. Not only Joint National Committee (JNC VI) and WHO-International Society of Hypertension (WHO-ISH 1999), but also Japanese Society of Hypertension (JSH 2000) are recommending the life-style modification for the initial treatment of hypertension.
众所周知,原发性高血压的发病机制是多因素的,环境和遗传因素及其相互作用在高血压发病机制中起着重要作用。环境因素包括自然环境因素,如天气、季节、温度、土壤和水,以及社会环境因素,如人际关系、社会经济地位、居住环境、教育程度、压力和生活方式。包括限制盐摄入、减轻体重、补充矿物质、有氧运动、限制饮酒、戒烟和缓解心理情绪压力在内的生活方式改变是抗高血压治疗的基本策略。不仅美国国家联合委员会(JNC VI)和世界卫生组织-国际高血压学会(WHO-ISH 1999),而且日本高血压学会(JSH 2000)都推荐将生活方式改变作为高血压初始治疗的方法。