Otsuka K
Department of Medicine, Tokyo Women's Medical University, School of Medicine, Daini Hospital.
Nihon Rinsho. 2001 May;59(5):983-91.
In the past 5 years several epidemiologic studies have demonstrated that sleep-related breathing disorders are an independent risk factor for hypertension, probably resulting from a combination of repetitive episodes of hypoxia, hypercapnea, arousals, and a striking surge in sympathetic excitation, and altered baroreflex control during sleep. Obstructive sleep apnea (OSA) may lead to the cardiac arrhythmias and myocardial ischemia and it is a possible risk factor for stroke. We confirmed that nasal CPAP has been shown to lower blood pressure in some hypertensive OSA patients. Early recognition and treatment of sleep-apnea may improve cardiovascular function.
在过去5年中，多项流行病学研究表明，睡眠呼吸障碍是高血压的独立危险因素，这可能是由于反复出现的低氧血症、高碳酸血症、觉醒以及睡眠期间交感神经兴奋显著增强和压力反射控制改变共同作用的结果。阻塞性睡眠呼吸暂停（OSA）可能导致心律失常和心肌缺血，并且是中风的一个潜在危险因素。我们证实，鼻持续气道正压通气（CPAP）已被证明可降低部分高血压OSA患者的血压。早期识别和治疗睡眠呼吸暂停可能改善心血管功能。
