Bissett S A, Lamb M, Ward C R
Department of Clinical Studies, School of Veterinary Medicine, The University of Pennsylvania, Philadelphia 19104, USA.
J Am Vet Med Assoc. 2001 May 15;218(10):1590-2, 1580. doi: 10.2460/javma.2001.218.1590.
Four cats with considerable peritoneal effusion and corresponding hyponatremia and hyperkalemia were evaluated. The Na:K ratio in all cats was < 25, which is suggestive of adrenal insufficiency. An ACTH stimulation test was performed on 3 cats for evaluation of adrenal gland function. Serum cortisol and aldosterone concentrations did not support a diagnosis of adrenal gland insufficiency. In 1 cat, histologic evaluation of the adrenal glands at necropsy also failed to support a diagnosis of hypoadrenocorticism. On the basis of these findings, and because hyponatremia and hyperkalemia could not be readily explained by another cause, the electrolyte abnormalities were presumed to be secondary to peritoneal effusion.
对4只伴有大量腹腔积液及相应低钠血症和高钾血症的猫进行了评估。所有猫的钠钾比均<25，提示肾上腺功能不全。对3只猫进行了促肾上腺皮质激素刺激试验以评估肾上腺功能。血清皮质醇和醛固酮浓度不支持肾上腺功能不全的诊断。在1只猫中，尸检时对肾上腺的组织学评估也不支持肾上腺皮质功能减退的诊断。基于这些发现，并且由于低钠血症和高钾血症无法轻易用其他原因解释，推测电解质异常继发于腹腔积液。
