Williams F L, Lang G A, Mage D T
Department of Epidemiology and Public Health, Ninewells Hospital and Medical School, Dundee.
Scott Med J. 2001 Apr;46(2):43-7. doi: 10.1177/003693300104600206.
Using a cohort study of all deaths in infants under 12 months in Dundee born between 1882-91 we set out to compare the aetiology of sudden unexpected infant deaths in Dundee at the end of the 19th Century with the aetiology of present day Sudden Infant Death Syndrome (SIDS). During 1882-1891, 361 infants died suddenly and unexpectedly and without obvious cause while in bed with their parents. The sex ratio of deaths was even (0.51 male) whereas the typical male fraction of SIDS today is 0.61. The mean age at death was almost two and one-half weeks younger in the Dundee cohort than for SIDS in modern Scotland. The infants in the Dundee cohort were discovered more frequently early in the morning than is typical. Their social class distribution was different in that no overlying cases were found in the higher classes whereas SIDS affects all classes. The overlying rate for illegitimate infants was lower than that reported for SIDS today. The epidemiological characteristics of the Dundee cohort and of those dying from present day SIDS differ considerably. The Dundee cohort apparently died from overlying rather than from SIDS as it is classified today. Present day advice that co-sleeping is safe should be given more cautiously until the safety of co-sleeping is resolved. It might be prudent to inform parents that co-sleeping is a risk factor for SIDS and that it should therefore be avoided.
我们利用一项队列研究，对1882年至1891年间在邓迪出生的12个月以下婴儿的所有死亡情况进行分析，旨在比较19世纪末邓迪婴儿意外猝死的病因与当今婴儿猝死综合征（SIDS）的病因。在1882年至1891年间，有361名婴儿在与父母同床时突然意外死亡，且无明显病因。死亡的性别比例均衡（男性占0.51），而如今SIDS中典型的男性比例为0.61。邓迪队列中婴儿的平均死亡年龄比现代苏格兰SIDS婴儿的平均死亡年龄小近两周半。邓迪队列中的婴儿在清晨被发现的频率高于通常情况。他们的社会阶层分布有所不同，即上层阶级未发现蒙被致死的案例，而SIDS会影响所有阶层。非婚生婴儿的蒙被致死率低于如今报道的SIDS致死率。邓迪队列与当今死于SIDS的人群的流行病学特征有很大差异。邓迪队列中的婴儿显然死于蒙被致死，而非如今所定义的SIDS。在同床睡眠的安全性问题得到解决之前，应更加谨慎地给出当今同床睡眠安全的建议。告知父母同床睡眠是SIDS的一个风险因素，因此应该避免，或许是谨慎之举。
