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非裔美国和白人老年社区居民在CERAD神经心理成套测验中的表现。

Performance of elderly African American and White community residents on the CERAD Neuropsychological Battery.

作者信息

Fillenbaum G G, Heyman A, Huber M S, Ganguli M, Unverzagt F W

机构信息

Center for the Study of Aging and Human Development, Duke University, Medical Center, Durham, North Carolina 27710, USA.

出版信息

J Int Neuropsychol Soc. 2001 May;7(4):502-9. doi: 10.1017/s1355617701744062.

Abstract

The CERAD Neuropsychological Battery, includes 7 measures: Verbal Fluency; Modified Boston Naming; Mini-Mental State: Word List Learning, Recall and Recognition; Constructional Praxis. It was originally developed to evaluate patients with a clinical diagnosis of Alzheimer's disease, but is increasingly used in epidemiological studies of the incidence and prevalence of dementia in the elderly. The current study reports norms for African American and White representative community residents 71 years of age and older in North Carolina, and compares performance with that of African Americans in Indianapolis and with Whites in the Monongahela Valley, Pennsylvania. For all 3 studies, increased education and younger age was related to better performance on each of the 7 measures. Sex differences, when present, tended to favor women. Although on average African Americans performed more poorly than Whites, with demographic characteristics controlled, no significant racial differences were found in the North Carolina sample. Both African American and White participants in North Carolina performed more poorly than their racial counterparts in the other 2 studies, possibly because of selection-induced differences in health and educational status. Nevertheless, the use of an identical evaluation battery, such as the CERAD neuropsychologic instrument, facilitates comparisons not otherwise possible, and should be encouraged.

摘要

CERAD神经心理成套测验包括7项测评:言语流畅性;改良波士顿命名法;简易精神状态检查表:单词表学习、回忆与识别;结构运用能力。它最初是为评估临床诊断为阿尔茨海默病的患者而开发的,但越来越多地用于老年人痴呆发病率和患病率的流行病学研究。本研究报告了北卡罗来纳州71岁及以上非裔美国人和白人代表性社区居民的常模,并将其表现与印第安纳波利斯的非裔美国人以及宾夕法尼亚州莫农加希拉山谷的白人进行了比较。在所有这3项研究中,受教育程度的提高和年龄的降低与7项测评中的每一项表现更好相关。存在性别差异时,往往对女性有利。尽管平均而言非裔美国人的表现比白人差,但在控制了人口统计学特征后,在北卡罗来纳州的样本中未发现显著的种族差异。北卡罗来纳州的非裔美国人和白人参与者的表现均比其他两项研究中的同种族参与者差可能是由于健康和教育状况方面的选择导致的差异。然而,使用相同的评估成套测验,如CERAD神经心理测验工具,有助于进行其他情况下无法进行的比较,应该予以鼓励。

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