Prytherch D R, Ridler B M, Beard J D, Earnshaw J J
St. Mary's Hospital, Portsmouth, UK.
Eur J Vasc Endovasc Surg. 2001 Jun;21(6):477-83. doi: 10.1053/ejvs.2001.1369.
The aim was to model vascular surgical outcome in a national study using POSSUM scoring.
One hundred and twenty-one British and Irish surgeons completed data questionnaires on patients undergoing arterial surgery under their care (mean 12 patients, range 1-49) in May/June 1998. A total of 1480 completed data records were available for logistic regression analysis using P-POSSUM methodology. Information collected included all POSSUM data items plus other factors thought to have a significant bearing on patient outcome: "extra items". The main outcome measures were death and major postoperative complications. The data were checked and inconsistent records were excluded. The remaining 1313 were divided into two sets for analysis. The first "training" set was used to obtain logistic regression models that were applied prospectively to the second "test" dataset.
using POSSUM data items alone, it was possible to predict both mortality and morbidity after vascular reconstruction using P-POSSUM analysis. The addition of the "extra items" found significant in regression analysis did not significantly improve the accuracy of prediction. It was possible to predict both mortality and morbidity derived from the preoperative physiology components of the POSSUM data items alone.
this study has shown that P-POSSUM methodology can be used to predict outcome after arterial surgery across a range of surgeons in different hospitals and could form the basis of a national outcome audit. It was also possible to obtain accurate models for both mortality and major morbidity from the POSSUM physiology scores alone.
在一项全国性研究中,使用POSSUM评分法对血管外科手术结果进行建模。
1998年5月/6月,121名英国和爱尔兰外科医生完成了关于其负责的接受动脉手术患者的数据问卷(平均每位医生12例患者,范围为1 - 49例)。共有1480份完整的数据记录可用于采用P-POSSUM方法进行逻辑回归分析。收集的信息包括所有POSSUM数据项以及其他被认为对患者预后有重大影响的因素:“额外项目”。主要结局指标为死亡和术后主要并发症。对数据进行检查,并排除不一致的记录。将剩余的1313份记录分为两组进行分析。第一组“训练”数据集用于获得逻辑回归模型,该模型被前瞻性地应用于第二组“测试”数据集。
仅使用POSSUM数据项,通过P-POSSUM分析就有可能预测血管重建后的死亡率和发病率。在回归分析中发现显著的“额外项目”的加入并没有显著提高预测的准确性。仅使用POSSUM数据项中的术前生理成分就有可能预测死亡率和发病率。
本研究表明,P-POSSUM方法可用于预测不同医院众多外科医生进行动脉手术后的结果,并可作为全国性结局审计的基础。仅从POSSUM生理评分中也有可能获得死亡率和主要发病率的准确模型。