• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

EGF mutant receptor vIII as a molecular target in cancer therapy.

作者信息

Kuan C T, Wikstrand C J, Bigner D D

机构信息

Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

Endocr Relat Cancer. 2001 Jun;8(2):83-96. doi: 10.1677/erc.0.0080083.

DOI:10.1677/erc.0.0080083
PMID:11397666
Abstract
摘要

相似文献

1
EGF mutant receptor vIII as a molecular target in cancer therapy.表皮生长因子（EGF）突变受体vIII作为癌症治疗中的分子靶点。
Endocr Relat Cancer. 2001 Jun;8(2):83-96. doi: 10.1677/erc.0.0080083.
2
Towards an immunotherapy for p185HER2 overexpressing tumors.针对p185HER2过表达肿瘤的免疫疗法。
Adv Exp Med Biol. 1994;353:83-94. doi: 10.1007/978-1-4615-2443-4_9.
3
EGFRvIII as a promising target for antibody-based brain tumor therapy.表皮生长因子受体III型变异体（EGFRvIII）作为基于抗体的脑肿瘤治疗的一个有前景的靶点。
Brain Tumor Pathol. 2000;17(2):71-8. doi: 10.1007/BF02482738.
4
Growth factor receptors as targets for antitumor therapy with monoclonal antibodies.生长因子受体作为单克隆抗体抗肿瘤治疗的靶点。
Prog Allergy. 1988;45:147-60. doi: 10.1159/000416378.
5
Therapeutic antibodies.
Curr Mol Med. 2004 Aug;4(5):539-47. doi: 10.2174/1566524043360483.
6
[Antibodies as specific tumor therapy agents. Wishful thinking or reality?].[抗体作为特异性肿瘤治疗药物。是痴心妄想还是现实？]
Internist (Berl). 1997 Nov;38(11):1055-62. doi: 10.1007/s001080050117.
7
The EGF receptor system as a target for antitumor therapy.作为抗肿瘤治疗靶点的表皮生长因子受体系统
Cancer Invest. 1991;9(5):553-62. doi: 10.3109/07357909109018953.
8
Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: targeting with a single chain antibody variable domain isolated by phage display.针对突变型表皮生长因子受体的重组免疫毒素：利用噬菌体展示分离的单链抗体可变区进行靶向
Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14815-20. doi: 10.1073/pnas.93.25.14815.
9
Growth factor receptor monoclonal antibodies and cancer immunotherapy.生长因子受体单克隆抗体与癌症免疫疗法。
J Natl Cancer Inst. 1989 Nov 1;81(21):1600-1. doi: 10.1093/jnci/81.21.1600.
10
Human cancer detection and immunotherapy with conjugated and non-conjugated monoclonal antibodies.使用偶联和非偶联单克隆抗体进行人类癌症检测与免疫治疗。
Anticancer Res. 1996 Mar-Apr;16(2):661-74.

引用本文的文献

1
Computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy.3-(4-(4-(1,3,4-恶二唑-2-基)-1-咪唑-2-基)苯基)-1,2,4-恶二唑衍生物作为有效的表皮生长因子受体抑制剂的计算设计、合成及评估：一种抗癌治疗的前瞻性策略
RSC Med Chem. 2024 Apr 11;15(5):1626-1639. doi: 10.1039/d4md00055b. eCollection 2024 May 22.
2
Potential Diagnostic and Clinical Significance of Selected Genetic Alterations in Glioblastoma.胶质母细胞瘤中特定基因改变的潜在诊断和临床意义
Int J Mol Sci. 2024 Apr 18;25(8):4438. doi: 10.3390/ijms25084438.
3
Novel biomolecules in targeted cancer therapy: a new approach towards precision medicine.
靶向癌症治疗中的新型生物分子：精准医学的新方法。
Med Oncol. 2023 Oct 7;40(11):323. doi: 10.1007/s12032-023-02168-6.
4
Allosteric activation of preformed EGF receptor dimers by a single ligand binding event.配体结合事件诱导预先形成的表皮生长因子受体二聚体的变构激活。
Front Endocrinol (Lausanne). 2022 Nov 30;13:1042787. doi: 10.3389/fendo.2022.1042787. eCollection 2022.
5
Identification of a novel peptide ligand for the cancer-specific receptor mutation EGFRvIII using high-throughput sequencing of phage-selected peptides.利用噬菌体选择肽的高通量测序鉴定新型针对 EGFRvIII 突变的肿瘤特异性受体肽配体。
Sci Rep. 2022 Dec 1;12(1):20725. doi: 10.1038/s41598-022-25257-4.
6
Multifunctional nanocarriers for delivering siRNA and miRNA in glioblastoma therapy: advances in nanobiotechnology-based cancer therapy.用于胶质母细胞瘤治疗中递送siRNA和miRNA的多功能纳米载体：基于纳米生物技术的癌症治疗进展
3 Biotech. 2022 Nov;12(11):301. doi: 10.1007/s13205-022-03365-2. Epub 2022 Sep 30.
7
MicroRNAs as the critical regulators of cell migration and invasion in thyroid cancer.微小RNA作为甲状腺癌中细胞迁移和侵袭的关键调节因子。
Biomark Res. 2022 Jun 4;10(1):40. doi: 10.1186/s40364-022-00382-4.
8
Brain Delivery of Nanomedicines: Trojan Horse Liposomes for Plasmid DNA Gene Therapy of the Brain.纳米药物的脑内递送：用于脑部质粒DNA基因治疗的特洛伊木马脂质体
Front Med Technol. 2020 Nov 16;2:602236. doi: 10.3389/fmedt.2020.602236. eCollection 2020.
9
Hippo Pathway in Regulating Drug Resistance of Glioblastoma.Hippo 通路在调控脑胶质母细胞瘤耐药中的作用。
Int J Mol Sci. 2021 Dec 14;22(24):13431. doi: 10.3390/ijms222413431.
10
Pre-clinical study of human umbilical cord mesenchymal stem cell transplantation for the treatment of traumatic brain injury: safety evaluation from immunogenic and oncogenic perspectives.人脐带间充质干细胞移植治疗创伤性脑损伤的临床前研究：从免疫原性和致癌性角度进行安全性评估。
Neural Regen Res. 2022 Feb;17(2):354-361. doi: 10.4103/1673-5374.317985.